Last reviewed on RxList: 2/17/2017
Sumycin Side Effects Center

Last reviewed on RxList 12/21/2016

Sumycin (tetracycline hydrochloride) is an antibiotic used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, chlamydia, and others. Sumycin is available in generic form. Common side effects of Sumycin include:

Tell your doctor if you have serious side effects of Sumycin including:

  • sunburn (sun sensitivity),
  • nail discoloration,
  • muscle pain,
  • changes in the amount of urine,
  • brown or gray tooth discoloration,
  • numbness or tingling of the hands or feet,
  • unusual fatigue,
  • new signs of infection (e.g., persistent sore throat, fever, chills),
  • hearing changes (e.g., ringing in the ears, decreased hearing),
  • easy bruising or bleeding,
  • severe stomach or abdominal pain,
  • yellowing eyes or skin, or
  • dark urine.

The usual daily dose of Sumycin for adults is 500 mg twice/day or 250 mg four times/day for mild to moderate infections; higher doses may be required for severe infections. For children above eight years of age, usual daily dose of Sumycin is 10 to 20 mg/lb (25 to 50 mg/kg) body weight divided in four equal doses. Sumycin may interact with cholesterol-lowering medications, isotretinoin, tretinoin, antacids, bismuth subsalicylate (i.e. Pepto-Bismol), minerals (iron, zinc, calcium, magnesium, over-the-counter vitamin and mineral supplements), blood thinners, or penicillin antibiotics. Tell your doctor all medications you are taking. Sumycin is not recommended for use during pregnancy because of possible harm to a fetus. Women of childbearing age should use effective birth control while taking this medication. This medication passes into breast milk in very small amounts. While there have been no reports of harm to nursing infants, consult your doctor before breastfeeding.

Our Sumycin (Tetracycline Hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


About how much does an adult human brain weigh? See Answer
Sumycin Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe blistering, peeling, and red skin rash;
  • fever, chills, body aches, flu symptoms;
  • pale or yellowed skin, easy bruising or bleeding;
  • any signs of a new infection.

Common side effects may include:

  • nausea, vomiting, diarrhea, upset stomach, loss of appetite;
  • white patches or sores inside your mouth or on your lips;
  • swollen tongue, black or "hairy" tongue, trouble swallowing;
  • sores or swelling in your rectal or genital area; or
  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Sumycin (Tetracycline)


Digestive Disorders: Common Misconceptions See Slideshow
Sumycin Professional Information


Gastrointestinal: anorexia, epigastric distress, nausea, vomiting, diarrhea, bulky loose stools, stomatitis, sore throat, glossitis, black hairy tongue, dysphagia, hoarseness, enterocolitis, and inflammatory lesions (with candidal overgrowth) in the anogenital region, including proctitis and pruritus ani. Rare instances of esophagitis and esophageal ulceration have been reported in patients receiving particularly the capsule and also the tablet forms of tetracyclines. Most of the patients were reported to have medication immediately before going to bed (see DOSAGE AND ADMINISTRATION). These reactions have been caused by both the oral and parenteral administration of tetracyclines but are less frequent after parenteral use.

Skin and Skin Structures: maculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon. Onycholysis and discoloration of the nails have been reported rarely. Photosensitivity has occurred. (See WARNINGS).

Renal Toxicity: increases in BUN have been reported and are apparently dose-related. (See WARNINGS.)

Hepatic Cholestasis: has been reported rarely, and is usually associated with high dosage levels of tetracycline.

Hypersensitivity Reactions: Anaphylaxis; serum sickness-like reactions, as fever, rash, and arthralgia; urticaria, angioneurotic edema, anaphylactoid purpura, pericarditis, exacerbation of systemic lupus erythematosus.

Hematological: Blood: anemia, hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, neutropenia and eosinophilia have been reported.

Miscellaneous: Dizziness and headache have been reported.

When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of thyroid glands. No abnormalities of thyroid function are known to occur. Bulging fontanels in infants and intracranial hypertension in adults have been reported. (See PRECAUTIONS-General.)

Read the entire FDA prescribing information for Sumycin (Tetracycline)

© Sumycin Patient Information is supplied by Cerner Multum, Inc. and Sumycin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors