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Last reviewed on RxList: 10/17/2019

(solriamfetol) Tablets


SUNOSI contains solriamfetol, a dopamine and norepinephrine reuptake inhibitor (DNRI). Solriamfetol is a phenylalanine derivative with the systematic name (R)-2amino-3-phenylpropylcarbamate hydrochloride.

The molecular formula is C10H15N2O2Cl, and the molecular weight is 230.69.

The chemical structure is:

SUNOSI (solriamfetol) Structural Formula Illustration

Solriamfetol hydrochloride is a white to off-white solid that is freely soluble in water.

SUNOSI tablets are intended for oral administration. Each 75 mg SUNOSI film-coated tablet contains 75 mg solriamfetol (equivalent to 89.3 mg solriamfetol hydrochloride). Each 150 mg SUNOSI film-coated tablet contains 150 mg solriamfetol (equivalent to 178.5 mg solriamfetol hydrochloride). The inactive ingredients are hydroxypropyl cellulose and magnesium stearate. In addition, the film coating contains: iron oxide yellow, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.