Suprax vs. Amoxicillin

Are Suprax and Amoxicillin the Same Thing?

Suprax (cefixime) and amoxicillin are antibiotics used to treat different types of infections caused by bacteria.

Brand names of amoxicillin include Moxatag and Amoxil.

Suprax and amoxicillin are different types of antibiotics. Suprax is a cephalosporin antibiotic and amoxicillin is a penicillin-type antibiotic.

What Are Possible Side Effects of Suprax?

Common side effects of Suprax include:

  • stomach upset/pain,
  • diarrhea,
  • nausea,
  • constipation,
  • loss of appetite,
  • gas,
  • headache,
  • dizziness,
  • anxiety,
  • drowsiness,
  • increased night-time urination,
  • runny nose,
  • sore throat,
  • cough, or
  • vaginal itching or discharge.

Tell your doctor if you experience rare but very serious side effects of Suprax including:

  • severe stomach or abdominal pain,
  • persistent nausea or vomiting,
  • yellowing eyes or skin,
  • dark urine,
  • unusual tiredness,
  • new signs of infection (e.g., persistent sore throat, fever),
  • easy bruising or bleeding,
  • change in the amount of urine, or
  • mental/mood changes (such as confusion).

What Are Possible Side Effects of Amoxicillin?

Common side effects of Amoxicillin include:

  • mild headache (not a migraine),
  • pain or chest tightness,
  • pressure or heavy feeling in any part of your body,
  • weakness,
  • feeling hot or cold,
  • dizziness,
  • spinning sensation,
  • drowsiness,
  • nausea,
  • vomiting,
  • drooling,
  • unusual taste in your mouth after using nasal spray,
  • burning/numbness/pain/irritation in your nose or throat after using nasal spray, or
  • flushing (warmth, redness, or tingling under the skin).

What Is Suprax?

Suprax (cefixime) for Oral Suspension is a cephalosporin antibiotic used to treat many different types of infections caused by bacteria.

What Is Amoxicillin?

Amoxil (amoxicillin) is a penicillin-type antibiotic used to treat infections caused by bacteria that are B-lactamase negative (B-lactamase positive bacteria are usually resistant to Amoxil); these infections usually occur in the skin, lungs, urinary tract and eye, ears, nose, and throat. Amoxil is available as a generic drug termed amoxicillin. Amoxil may be combined with other drugs (for example, clavulanic acid [Augmentin]), to make the antibiotic more effective.

What Drugs Interact With Suprax?

Other drugs may interact with Suprax. Tell your doctor all prescription and over-the-counter medications and supplements you use. Suprax should be used only when prescribed during pregnancy. This drug passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breastfeeding.

What Drugs Interact With Amoxicillin?

Amoxil may interact with probenecid, blood thinners, other antibiotics, or sulfa drugs. Tell your doctor all medications and supplements you use. Treatment in pregnant women and women who are breastfeeding should be done with caution.

How Should Suprax Be Taken?

The recommended dosage of Suprax is 70 mg once monthly; some patients may benefit from a dosage of 140 mg once monthly, which is administered as two consecutive subcutaneous injections of 70 mg each.

How Should Amoxicillin Be Taken?

Amoxil is available in many preparations (capsules, tablets, chewable tablets, powder for oral suspension and pediatric oral suspension).


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Lupin Pharmaceuticals, Inc. Suprax Product Information.

Medscape. Amoxil, Moxatag Product Information.

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