Medical Editor: John P. Cunha, DO, FACOEP
Suprenza (phentermine hydrochloride) orally disintegrating tablet (ODT) is a sympathomimetic amine anorectic indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for patients with an initial body mass index ≥ 30 kg/m², or ≥ 27 kg/m² in the presence of other risk factors such as controlled hypertension, diabetes, or hyperlipidemia (high fat levels in the blood). Side effects of Suprenza include dizziness, dry mouth, trouble sleeping (insomnia), irritability, nausea, vomiting, diarrhea, constipation, restlessness, euphoria, feeling uneasy, difficulty breathing, weakness, swelling of the ankles and feet, increased blood pressure, fatigue, headache, unpleasant taste in the mouth, changes in sex drive, or impotence.
Dosage should be individualized to obtain an adequate response with the lowest effective dose. When tolerance to the effect of Suprenza develops, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued. Suprenza is contraindicated during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. It is not known if Suprenza is excreted in human milk; however, other amphetamines are present in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Our Suprenza (phentermine hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
The following adverse reactions are described, or described in greater detail, in other sections:
- Primary pulmonary hypertension [see WARNINGS AND PRECAUTIONS]
- Valvular heart disease [see WARNINGS AND PRECAUTIONS]
- Effect on the ability to engage in potentially hazardous tasks [see WARNINGS AND PRECAUTIONS]
- Withdrawal effects following prolonged high dosage administration [see Drug Abuse and Dependence)]
The following adverse reactions to phentermine have been identified:
Central Nervous System
Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.
Read the entire FDA prescribing information for Suprenza (phentermine hydrochloride)