Suprenza Side Effects Center

Last updated on RxList: 2/16/2022
Suprenza Side Effects Center

What Is Suprenza?

Suprenza (phentermine hydrochloride) orally disintegrating tablet (ODT) is a sympathomimetic amine anorectic indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for patients with an initial body mass index ≥ 30 kg/m², or ≥ 27 kg/m² in the presence of other risk factors such as controlled hypertension, diabetes, or hyperlipidemia (high fat levels in the blood).

What Are Side Effects of Suprenza?

Side effects of Suprenza include:

  • dizziness,
  • dry mouth,
  • trouble sleeping (insomnia),
  • irritability,
  • nausea,
  • vomiting,
  • diarrhea,
  • constipation,
  • restlessness,
  • euphoria,
  • feeling uneasy,
  • difficulty breathing,
  • weakness,
  • swelling of the ankles and feet,
  • increased blood pressure,
  • fatigue,
  • headache,
  • unpleasant taste in the mouth,
  • changes in sex drive, or
  • impotence

Dosage for Suprenza

Dosage should be individualized to obtain an adequate response with the lowest effective dose. When tolerance to the effect of Suprenza develops, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued.

Suprenza During Pregnancy or Breastfeeding

Suprenza is contraindicated during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. It is not known if Suprenza is excreted in human milk; however, other amphetamines are present in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Additional Information

Our Suprenza (phentermine hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Suprenza Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • feeling short of breath, even with mild exertion;
  • chest pain, feeling like you might pass out;
  • swelling in your ankles or feet;
  • pounding heartbeats or fluttering in your chest;
  • tremors, feeling restless, trouble sleeping;
  • unusual changes in mood or behavior; or
  • increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed.

Common side effects may include:

  • itching;
  • dizziness, headache;
  • dry mouth, unpleasant taste;
  • diarrhea, constipation, stomach pain; or
  • increased or decreased interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Suprenza Professional Information


The following adverse reactions are described, or described in greater detail, in other sections:

The following adverse reactions to phentermine have been identified:


Primary pulmonary hypertension and/or regurgitant cardiac valvular disease, palpitation, tachycardia, elevation of blood pressure, ischemic events.

Central Nervous System

Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis.


Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.




Impotence, changes in libido.

Read the entire FDA prescribing information for Suprenza (phentermine hydrochloride)

© Suprenza Patient Information is supplied by Cerner Multum, Inc. and Suprenza Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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