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Tagamet vs. Prilosec

Reviewed on 4/15/2019

Are Tagamet and Prilosec the Same Thing?

Tagamet (cimetidine) and Prilosec (lansoprazole) are used to treat and prevent certain types of ulcer, to treat conditions that cause the stomach to produce too much acid, and to treat gastroesophageal reflux disease (GERD).

Prilosec is also used to treat erosive esophagitis and Zollinger-Ellison syndrome.

Tagamet and Prilosec belong to different drug classes. Tagamet is a histamine receptor antagonist and Prilosec is a proton pump inhibitor (PPI).

Both Tagamet and Prilosec are available over-the-counter (OTC) and as generics.

Side effects of Tagamet and Prilosec that are similar include dizziness, headache, nausea, diarrhea, or constipation.

Side effects of Tagamet that are different from Prilosec include drowsiness, depression, agitation, breast swelling or tenderness (in men), joint or muscle pain, skin rash,

Side effects of Prilosec that are different from Tagamet include stomach pain, fast or irregular heart rate, watery or bloody diarrhea, muscle cramps or weakness, jerky muscle movements, confusion, or feeling jittery.

Both Tagamet and Prilosec may interact with ketoconazole or blood thinners.

Tagamet may also interact with antacids, or antidepressants.

Prilosec may also interact with sucralfate, ampicillin, atazanavir, digoxin, iron, methotrexate, theophylline, or diuretics (water pills).

What Are Possible Side Effects of Tagamet?

Common side effects of Tagamet include:

Tell your doctor if you experience unlikely but serious side effects of Tagamet Injection including:

  • decreased sweating,
  • fast/irregular heartbeat,
  • mental/mood changes (such as confusion, hallucinations, agitation, nervousness, unusual excitement),
  • difficulty urinating, or
  • decreased sexual ability.

What Are Possible Side Effects of Prilosec?

Common side effects of Prilosec include:

  • headache,
  • nausea,
  • vomiting,
  • diarrhea,
  • stomach pain,
  • gas,
  • constipation,
  • fever, or
  • cold symptoms (stuffy nose, sneezing, and sore throat).

What Is Tagamet?

Tagamet (cimetidine) is a histamine receptor antagonist used to treat and prevent certain types of ulcer, and to treat conditions that cause the stomach to produce too much acid. Tagamet is also used to treat gastroesophageal reflux disease (GERD), when stomach acid backs up into the esophagus and causes heartburn.

What Is Prilosec?

Prilosec (omeprazole) is a proton pump inhibitor (PPI) used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome, which are all caused by stomach acid.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow

What Drugs Interact With Tagamet?

Tagamet may interact with amantadine, quinidine, antihistamines, decongestants, appetite suppressants, phenothiazines, or antidepressants. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy, Tagamet should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Prilosec?

Prilosec may interact with digoxin, diuretics (water pills), blood thinners, antifungal medications such as ketoconazole, antibiotics such as ampicillin, iron, or methotrexate, and HIV or AIDS medications such as atazanavir and nelfinavir.

Prilosec may also interact with bosentan, cilostazol, clopidogrel, cyclosporine, diazepam, disulfiram, St. John's wort, tacrolimus, or seizure medications.

How Should Tagamet Be Taken?

Dose of Tagamet depends on the condition being treated and the patient's response to the medication.

How Should Prilosec Be Taken?

The recommended adult oral dose of Prilosec ranges from 20 mg to 60 mg once daily, depending on the condition being treated. For maximal efficacy, Prilosec tablets should be taken before meals, swallowed whole and should not be crushed, chewed or opened.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

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If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
SOURCE:

Prestige Consumer Healthcare. Tagamet Product Information.

https://www.tagamet.com/

FDA. Prilosec Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf
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