Takayasu disease: A chronic inflammatory disease of the aorta and its branch arteries. The cause is unknown. The disease is most common in young women of Asian descent and usually begins between 10 and 30 years of age. Symptoms include painful, cool, or blanched extremities, dizziness, headaches, chest and abdominal pain, and low-grade fever. The blood pressure is often high. The sedimentation rate (sed rate) may be elevated, reflecting inflammation. The diagnosis is confirmed by an angiogram of the arteries (arteriogram) showing abnormally narrowed and constricted arteries. The disease is treated with corticosteroids and immunosuppressive drugs when needed. Also known as Takayasu arteritis; Martorell syndrome; pulseless disease; and aortic arch syndrome.