Talicia vs. Sumycin

Are Sumycin and Talicia the Same Thing?

Talicia (omeprazole magnesium, amoxicillin and rifabutin) and Sumycin (tetracycline hydrochloride) are used to treat Helicobacter pylori infection in adults.

Sumycin is given in combination with other medications to treat Helicobacter pylori infection. Sumycin is also used to treat many different bacterial infections, such as urinary tract infections (UTIs), acne, gonorrhea, chlamydia, and others.

Talicia and Sumycin belong to different drug classes. Talicia is a combination of a proton pump inhibitor, a penicillin-class antibiotic, and a rifamycin antibacterial and Sumycin is a tetracycline antibiotic.

Side effects of Talicia and Sumycin that are similar include diarrhea, headache, nausea, and vomiting.

Side effects of Talicia that are different from Sumycin include abdominal pain, abnormally colored urine, rash, heartburn/indigestion, mouth and throat pain, and vaginal yeast infection.

Side effects of Sumycin that are different from Talicia include stomach upset, loss of appetite, white patches or sores inside your mouth or on your lips, swollen tongue, black hairy tongue, sore throat, trouble swallowing, dizziness, sores or swelling in your rectal or genital area, and vaginal itching or discharge.

Both Talicia and Sumycin may interact with blood thinners.

Talicia may also interact with voriconazole, St. John's wort, rifampin, ritonavir, fluconazole, posaconazole, itraconazole, clopidogrel, citalopram, cilostazol, phenytoin, diazepam, antiretrovirals, protease inhibitors, probenecid, allopurinol, methotrexate, digoxin, cyclosporine, disulfiram, and hormonal contraceptives.

Sumycin may also interact with cholesterol-lowering medications, isotretinoin, tretinoin, antacids, bismuth subsalicylate (i.e. Pepto-Bismol), minerals (iron, zinc, calcium, magnesium, over-the-counter vitamin and mineral supplements), and penicillin antibiotics.

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What Are Possible Side Effects of Talicia?

Common side effects of Talicia include:

  • diarrhea,
  • headache,
  • nausea,
  • abdominal pain,
  • abnormally colored urine,
  • rash,
  • heartburn/indigestion,
  • mouth and throat pain,
  • vomiting, and
  • vaginal yeast infection

What Are Possible Side Effects of Sumycin?

Common side effects of Sumycin include:

  • nausea,
  • vomiting,
  • diarrhea,
  • stomach upset,
  • loss of appetite,
  • white patches or sores inside your mouth or on your lips,
  • swollen tongue,
  • black hairy tongue,
  • sore throat,
  • trouble swallowing,
  • dizziness,
  • headache,
  • sores or swelling in your rectal or genital area, or
  • vaginal itching or discharge.

Tell your doctor if you have serious side effects of Sumycin including:

  • sunburn (sun sensitivity),
  • nail discoloration,
  • muscle pain,
  • changes in the amount of urine,
  • brown or gray tooth discoloration,
  • numbness or tingling of the hands or feet,
  • unusual fatigue,
  • new signs of infection (e.g., persistent sore throat, fever, chills),
  • hearing changes (e.g., ringing in the ears, decreased hearing),
  • easy bruising or bleeding,
  • severe stomach or abdominal pain,
  • yellowing eyes or skin, or
  • dark urine.

What is Talicia?

Talicia (omeprazole magnesium, amoxicillin and rifabutin) is a three-drug combination of:

  • a proton pump inhibitor,
  • a penicillin-class antibacterial, and
  • a rifamycin antibacterial indicated for the treatment of Helicobacter pylori infection in adults.

What is Sumycin?

Sumycin (tetracycline hydrochloride) is an antibiotic used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, chlamydia, and others.

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What Drugs Interact With Talicia?

Talicia may interact with other medicines such as:

  • voriconazole,
  • St. John's wort,
  • rifampin,
  • ritonavir,
  • fluconazole,
  • posaconazole,
  • itraconazole,
  • clopidogrel,
  • citalopram,
  • cilostazol,
  • phenytoin,
  • diazepam,
  • antiretrovirals,
  • protease inhibitors,
  • probenecid,
  • allopurinol,
  • oral anticoagulants,
  • methotrexate,
  • digoxin,
  • cyclosporine,
  • disulfiram, and
  • hormonal contraceptives

What Drugs Interact With Sumycin?

Sumycin may interact with cholesterol-lowering medications, isotretinoin, tretinoin, antacids, bismuth subsalicylate (i.e. Pepto-Bismol), minerals (iron, zinc, calcium, magnesium, over-the-counter vitamin and mineral supplements), blood thinners, or penicillin antibiotics. Tell your doctor all medications you are taking. Sumycin is not recommended for use during pregnancy because of possible harm to a fetus. Women of childbearing age should use effective birth control while taking this medication. This medication passes into breast milk in very small amounts. While there have been no reports of harm to nursing infants, consult your doctor before breastfeeding.

Sumycin may also interact with colchicine, itraconazole, omeprazole, ranitidine, bismuth citrate, sildenafil, tadalafil, vardenafil, tolterodine, steroids, or insulin or oral diabetes medications.

How Should Talicia Be Taken?

The dosage of Talicia is four (4) capsules every 8 hours with food for 14 days.

How Should Sumycin Be Taken?

The usual daily dose of Sumycin for adults is 500 mg twice/day or 250 mg four times/day for mild to moderate infections; higher doses may be required for severe infections. For children above eight years of age, usual daily dose of Sumycin is 10 to 20 mg/lb (25 to 50 mg/kg) body weight divided in four equal doses.

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References
RedHill Pharma. Talicia Product Information.

https://www.redhillbio.com › talicia

Dailymed. Sumycin Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a684589-7e74-4435-ad19-dbd35175b4c9

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