Reviewed on 6/11/2021
Other Name(s):

Bergamota, Citrus nobilis, Citrus reticulate, Culate Mandarin, Gan Ju, Mandarin, Mandarin Orange, Mandarina, Mandarina, Mandarina, Mandarine Orange, Mandarinen, Mandarinenbaum, Mandarinier, Ponkan, Santara, Småcitrus, Swatow Orange, Tangerina.


Tangerine is a citrus fruit that grows in tropical areas of Asia.

People take tangerine peel by mouth for asthma, indigestion, clogged arteries, cancer prevention, chemotherapy side effects, colon and rectal cancer, irritable bowel syndrome (IBS), liver disease, and lung cancer.

Tangerine fruit and peel can be eaten as a food. Tangerine fruit can also be made into a juice.

How does it work?

Tangerine might reduce the risk of cancer. The tangerine peel seems to stop the growth of, or increase the death of, cancer cells.


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Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Cancer. Early research suggests that eating a lot of oranges and/or tangerines is linked to a lower risk of developing a type of cancer called nasopharyngeal carcinoma. This type of cancer affects the area behind the nose, where it meets the throat.
  • Asthma.
  • Indigestion.
  • Clogged arteries.
  • Chemotherapy side effects.
  • Colon and rectal cancer.
  • Irritable bowel syndrome (IBS).
  • Liver disease.
  • Lung cancer.
  • Other conditions.
More evidence is needed to rate tangerine for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Tangerine is LIKELY SAFE when consumed in amounts found in foods. There isn't enough reliable information available about tangerine to know if it is safe when used as a medicine.


Next to red peppers, you can get the most vitamin C from ________________. See Answer

Special Precautions & Warnings

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking tangerine if you are pregnant or breast-feeding. Stay on the safe side and avoid use.


Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.

Some medications are changed and broken down by the liver. Tangerine might increase how quickly the liver breaks down these medications. In theory, taking tangerine along with medications that are broken down by the liver can decrease the effects of some medications. Before taking tangerine, talk to your healthcare provider if you are taking any medications that are changed by the liver.

Some medications changed by the liver include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.

Midazolam (Versed)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.

The body breaks down midazolam (Versed) to get rid of it. Tangerine might increase how quickly the body breaks down midazolam (Versed). In theory, taking tangerine along with midazolam (Versed) might decrease the effects of midazolam (Versed).


The appropriate dose of tangerine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for tangerine (in children/in adults). Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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