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Tazorac Cream

Last reviewed on RxList: 5/18/2018
Tazorac Cream Side Effects Center

Last reviewed on RxList 5/18/2018

Tazorac (tazarotene) cream or gel is a compound similar to vitamin A used to treat plaque psoriasis (psoriasis with scaly patches) and to treat facial acne. Another brand of tazarotene cream (Avage) is used to reduce the appearance of fine wrinkles on the face, mottled light and dark skin patches on the face, and benign facial lentigines (noncancerous freckles). Common side effects of Tazorac include:

  • application site reactions such as itching,
  • redness,
  • irritation,
  • burning,
  • stinging,
  • scaling,
  • peeling,
  • dry skin,
  • rash,
  • acne,
  • pain, or
  • inflammation of the lips.

Tell your doctor if you have serious side effects of Tazorac including:

  • severe skin irritation (burning, stinging, itching) after applying this medication;
  • severe redness or discomfort; or
  • swelling, warmth, oozing, or other signs of skin infection.

Dose of Tazorac depends on the condition being treated. For psoriasis: treatment starts with Tazorac 0.05% Gel, with strength increased to 0.1% if tolerated and medically indicated. Apply once a day, to psoriatic lesions, using enough to cover only the lesion with a thin film to no more than 20% of body surface area. For acne: Cleanse the face and apply a thin film of Tazorac Gel 0.1% once a day, to the skin where acne lesions appear. Tazorac may interact with diuretics (water pills), antibiotics, or phenothiazines. Tell your doctor all medications you are taking. Tazorac must not be used during pregnancy. It may harm a fetus. If you become pregnant or think you may be pregnant, tell your doctor. It is recommended that men and women using this medication use two effective forms of birth control (e.g., condoms and birth control pills) while taking this medication. It is not known if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Tazorac (tazarotene) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow
Tazorac Cream Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using tazarotene topical and call your doctor at once if you have:

  • severe skin irritation (pain, dryness, flaking, peeling, burning, stinging, itching) after applying the medicine;
  • blistering or peeling skin;
  • severe redness or discomfort; or
  • swelling, warmth, oozing, or other signs of skin infection.

Common side effects may include:

  • dry, scaly, or peeling skin;
  • skin pain, redness or burning; or
  • itching or other irritation of treated skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tazorac Cream (Tazarotene Cream)

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Tazorac Cream Professional Information

SIDE EFFECTS

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In human dermal safety trials, TAZORAC® Cream, 0.05% and 0.1% did not induce allergic contact sensitization, phototoxicity, or photoallergy.

Psoriasis

The most frequent adverse reactions reported with TAZORAC® Cream, 0.05% and 0.1% occurring in 10 to 23% of subjects, in descending order, included pruritus, erythema, and burning. Reactions occurring in greater than 1 to less than 10% of subjects, in descending order, included irritation, desquamation, stinging, contact dermatitis, dermatitis, eczema, worsening of psoriasis, skin pain, rash, hypertriglyceridemia, dry skin, skin inflammation, and peripheral edema.

TAZORAC® Cream, 0.1% was associated with a greater degree of local irritation than the 0.05% cream. The rates of irritation adverse reactions reported during psoriasis trials with TAZORAC® Cream, 0.1% were 0.1 0.4% higher than those reported for TAZORAC® Cream, 0.05%.

Acne

The most frequent adverse reactions reported during clinical trials with TAZORAC® Cream 0.1% in the treatment of acne, occurring in 10-30% of subjects, in descending order included desquamation, dry skin, erythema, and burning sensation. Reactions occurring in 1 to 5% of subjects included pruritus, irritation, face pain, and stinging.

Read the entire FDA prescribing information for Tazorac Cream (Tazarotene Cream)

Related Resources for Tazorac Cream

Read the Tazorac Cream User Reviews »

© Tazorac Cream Patient Information is supplied by Cerner Multum, Inc. and Tazorac Cream Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow

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