Tegretol vs. Depakote

Are Tegretol and Depakote the Same Thing?

Tegretol (carbamazepine) and Depakote (divalproex sodium) are anticonvulsants used to treat seizure and bipolar disorder.

Tegretol is also used to treat nerve pain such as trigeminal neuralgia and diabetic neuropathy.

Depakote is also used to treat migraine headaches.

What Are Possible Side Effects of Tegretol?

Common side effects of Tegretol include:

What Are Possible Side Effects of Depakote?

Common side effects of Depakote include:

SLIDESHOW

What Is Epilepsy? Symptoms, Causes, and Treatments See Slideshow

What Is Tegretol?

Tegretol (carbamazepine) is an anticonvulsant used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. Tegretol is also used to treat bipolar disorder. Tegretol is available in generic form.

What Is Depakote?

Depakote (divalproex sodium) is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. Generic Depakote (termed divalproex sodium) is available under several other names.

What Drugs Interact With Tegretol?

Tegretol may interact with other seizure medications, HIV or AIDS medications, antibiotics, antidepressants, medications to treat mental illness, or blood thinners.

Tegretol may also interact with theophylline, birth control pills or hormone replacement therapy, drugs to treat tuberculosis, antifungal medications, cancer medicines, heart or blood pressure medications, medicines to prevent organ transplant rejection, steroids, or thyroid replacement medications.

You may have increased seizures or unpleasant withdrawal symptoms if you stop using Tegretol suddenly.

What Drugs Interact With Depakote?

Depakote may interact with other seizure medications, HIV or AIDS medications, antibiotics, antidepressants, medications to treat mental illness, or blood thinners.

Depakote may also interact with phenobarbital, aspirin, rifampin, and tolbutamide.

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How Should Tegretol Be Taken?

The starting dose of Tegretol to treat epilepsy in adults and children over 12 years of age is 200 mg twice daily for tablets and XR tablets, or 1 tsp 4 times daily for suspension (400 mg/day). Usual maintenance dose is 800-1200 mg daily. The starting dose to treat trigeminal neuralgia is 100 mg twice daily for tablets or XR tablets, or ½ tsp 4 times daily for suspension, for a total daily dose of 200 mg. Control of pain is maintained in most patients with 400-800 mg daily. Consult your doctor for pediatric doses.

How Should Depakote Be Taken?

The recommended initial dose of Depakote to treat mania is 750 mg daily in divided doses. The dose of Depakote to treat epilepsy as monotherapy should be initiated at 10 to 15 mg/kg/day. The recommended starting dose of Depakote to treat migraines is 250 mg twice daily.

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References
Medical Editor: John P. Cunha, DO, FACOEP

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