Medical Editor: John P. Cunha, DO, FACOEP
Temovate (clobetasol propionate) Gel, 0.05% is a topical (for the skin) steroid used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Temovate Gel is available in generic form. Common side effects of Temovate Gel include burning, stinging, itching, dryness, redness, or skin rash at the application site when first applied to the skin. This should disappear in a few days as your body adjusts to Temovate Gel. Other side effects of Temovate Gel include dry or cracking skin, thinning or softening of your skin, skin rash or irritation around your mouth, swollen hair follicles, temporary hair loss, spider veins, changes in color of treated skin, blisters, pimples, crusting of treated skin, or stretch marks.
Temovate Gel is applied topically (on the skin) to the affected areas twice daily. Treatment should be limited to 2 consecutive weeks and amounts greater than 50 g/week should not be used. Temovate Gel may interact with other drugs. Tell your doctor all medications you use. During pregnancy, Temovate Gel should be used only when prescribed. It is unknown if this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breastfeeding.
Our Temovate (clobetasol propionate) Gel, 0.05% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.
Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- muscle weakness, feeling tired.
Less serious side effects may include:
- mild skin rash, itching, burning, or redness;
- dry or cracking skin;
- thinning or softening of your skin;
- skin rash or irritation around your mouth;
- swollen hair follicles;
- temporary hair loss;
- spider veins;
- changes in color of treated skin;
- blisters, pimples, or crusting of treated skin; or
- stretch marks.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Temovate Gel (Clobetasol Propionate Gel)
In a controlled trial with TEMOVATE Gel (clobetasol propionate gel) , the only reported adverse reaction that was considered to be drug related was a report of burning sensation (1.8% of treated patients).
In larger controlled clinical trials with other clobetasol propionate formulations, the most frequently reported adverse reactions have included burning, stinging, irritation, pruritus, erythema, folliculitis, cracking and fissuring of the skin, numbness of fingers, skin atrophy, and telangiectasia (all less than 2%).
The following additional local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with super-high potency corticosteroids such as TEMOVATE Gel (clobetasol propionate gel) . These reactions are listed in approximate decreasing order of occurrence: dryness, hypertrichosis, acnerform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, irritation, striae, and miliaria.
Read the entire FDA prescribing information for Temovate Gel (Clobetasol Propionate Gel)