Medical Reviewer: John P. Cunha, DO, FACOEP Last updated on RxList: 1/6/2022
Tessalon Side Effects Center

Pharmacy Editor: Omudhome Ogbru, PharmD

What Are Tessalon Perles?

Tessalon Perles (benzonatate) is an oral non-narcotic oral antitussive medication used for suppressing cough. A generic version of Tessalon Perles is available.

What Are Side Effects of Tessalon Perles?

Common side effects of Tessalon Perles include

Dosage for Tessalon Perles

The usual dose of Tessalon Perles is 100 mg three times daily.

What Drugs, Substances, or Supplements Interact with Tessalon Perles?

Tessalon Perles may interact with other medicines that make you sleepy (such as cold or allergy medicines, sedatives, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for seizures, depression, or anxiety). Tell your doctor all medications and supplements you use.

Tessalon Perles During Pregnancy and Breastfeeding

Use during pregnancy has not been adequately evaluated and it is not known whether Tessalon is secreted into breast milk. Tell your doctor if you are pregnant or breastfeeding before using Tessalon Perles.

Additional Information

Our Tessalon Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Tessalon Consumer Information

Stop taking this medicine and get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe drowsiness or dizziness;
  • confusion, hallucinations.
  • ongoing numbness or tingling in your mouth, throat, or face;
  • numbness in your chest;
  • a choking feeling;
  • chills; or
  • burning in your eyes.

Some of these side effects may result from chewing or sucking on a benzonatate capsule.

Common side effects may include:

  • headache, dizziness;
  • nausea, upset stomach;
  • constipation;
  • itching, rash; or
  • stuffy nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tessalon (Benzonatate Capsules)


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Tessalon Professional Information


Potential Adverse Reactions to TESSALON may include:

Hypersensitivity reactions including bronchospasm, laryngospasm, cardiovascular collapse possibly related to local anesthesia from chewing or sucking the capsule.

CNS: sedation; headache; dizziness; mental confusion; visual hallucinations.

GI: constipation; nausea; GI upset.

Dermatologic: pruritus; skin eruptions.

Other: nasal congestion; sensation of burning in the eyes; vague “chilly” sensation; numbness of the chest; hypersensitivity.

Deliberate or accidental overdose has resulted in death, particularly in children.

Read the entire FDA prescribing information for Tessalon (Benzonatate Capsules)

© Tessalon Patient Information is supplied by Cerner Multum, Inc. and Tessalon Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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