Thyro-Tabs

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 10/6/2021
Thyro-Tabs Side Effects Center

What Is Thyro-Tabs?

Thyro-Tabs (levothyroxine sodium) tablets are L-thyroxine (T4) indicated as replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) con genital or acquired hypothyroidism; and as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.

What Are Side Effects of Thyro-Tabs?

Common side effects of Thyro-Tabs are primarily those of hyperthyroidism due to therapeutic overdosage including:

Dosage for Thyro-Tabs

Administer a dose of Thyro-Tabs once daily, preferably on an empty stomach, one-half to one hour before breakfast. The starting dose of Thyro-Tabs depends on a variety of factors, including age, body weight, cardiovascular status, and concomitant medications. Peak therapeutic effect may not be attained for 4-6 weeks.

What Drugs, Substances, or Supplements Interact with Thyro-Tabs?

Thyro-Tabs may interact with calcium carbonate, ferrous sulfate, orlistat, bile acid sequestrants, ion exchange resins, proton pump inhibitors (PPIs), sucralfate, antacids, clofibrate, estrogen-containing oral contraceptives, estrogens (oral), heroin/methadone, 5-fluorouracil, mitotane, tamoxifen, androgens, anabolic steroids, glucocorticoids, slow-release nicotinic acid, salicylates, carbamazepine, furosemide, heparin, hydantoins, nonsteroidal anti-inflammatory drugs (NSAIDs), phenobarbital, rifampin, beta-adrenergic antagonists, glucocorticoids, and amiodarone. Tell your doctor all medications and supplements you use.

Thyro-Tabs During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Thyro-Tabs. There are risks to the mother and fetus associated with untreated hypothyroidism in pregnancy. Since TSH levels may increase during pregnancy, TSH should be monitored and Thyro-Tabs dosage adjusted during pregnancy. Thyro-Tabs pass into breast milk but its effects on nursing infants are unknown. Consult your doctor before breastfeeding.

Additional Information

Our Thyro-Tabs (levothyroxine sodium) Tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Hyperthyroidism Symptoms and Treatment See Slideshow
Thyro-Tabs Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fast or irregular heartbeats;
  • chest pain, pain spreading to your jaw or shoulder;
  • shortness of breath;
  • fever, hot flashes, sweating;
  • tremors, or if you feel unusually cold;
  • weakness, tiredness, sleep problems (insomnia);
  • memory problems, feeling depressed or irritable;
  • headache, leg cramps, muscle aches;
  • feeling nervous or irritable;
  • dryness of your skin or hair, hair loss;
  • irregular menstrual periods; or
  • vomiting, diarrhea, appetite changes, weight changes.

Certain side effects may be more likely in older adults.

Common side effects may include:

  • chest pain, irregular heartbeats;
  • shortness of breath;
  • headache, leg cramps, muscle pain or weakness;
  • tremors, feeling nervous or irritable, trouble sleeping;
  • increased appetite;
  • feeling hot;
  • weight loss;
  • changes in your menstrual periods;
  • diarrhea; or
  • skin rash, partial hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Thyro-Tabs (Levothyroxine Sodium)

QUESTION

Where is the thyroid gland located? See Answer
Thyro-Tabs Professional Information

SIDE EFFECTS

Adverse reactions associated with THYRO-TABS therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see WARNINGS AND PRECAUTIONS , OVERDOSE]. They include the following:

  • General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating
  • Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia
  • Musculoskeletal: tremors, muscle weakness, muscle spasm
  • Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest
  • Respiratory: dyspnea
  • Gastrointestinal: diarrhea, vomiting, abdominal cramps, elevations in liver function tests
  • Dermatologic: hair loss, flushing, rash
  • Endocrine: decreased bone mineral density
  • Reproductive: menstrual irregularities, impaired fertility

Seizures have been reported rarely with the institution of levothyroxine therapy.

Adverse Reactions In Children

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height.

Hypersensitivity Reactions

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various gastrointestinal symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness, and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.

Read the entire FDA prescribing information for Thyro-Tabs (Levothyroxine Sodium)

© Thyro-Tabs Patient Information is supplied by Cerner Multum, Inc. and Thyro-Tabs Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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