Tigan Injection Side Effects Center

Last updated on RxList: 3/2/2022
Tigan Injection Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Tigan Injection?

Tigan (trimethobenzamide hydrochloride) Injectable is an anticholinergic drug used to treat nausea and vomiting. Tigan is available in generic form.

What Are Side Effects of Tigan Injection?

Common side effects of Tigan include:

  • drowsiness or dizziness,
  • headache,
  • depression,
  • disorientation, or
  • blurred vision.

Tell your doctor if you have serious side effects of Tigan including:

Dosage for Tigan Injection

Dosage of Tigan is adjusted according to the reason for therapy, severity of symptoms and the response of the patient.

What Drugs, Substances, or Supplements Interact with Tigan Injection?

Tigan may interact with other drugs that make you sleepy (such as cold medicine, pain medication, muscle relaxants, and medicine for seizures, depression or anxiety). Tell your doctor all medications and supplements you use.

Tigan Injection During Pregnancy or Breastfeeding

During pregnancy, Tigan should be taken only if prescribed. Tell your doctor if you are pregnant or could become pregnant during treatment. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Tigan (trimethobenzamide hydrochloride) Injectable Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Tigan Injection Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking trimethobenzamide and call your doctor at once if you have:

  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
  • trouble speaking or swallowing;
  • problems with thought or memory;
  • pain, stiffness, or unusual muscle spasm in your neck;
  • tremors, feeling restless or being unable to sit still;
  • jaundice (yellowing of the skin or eyes);
  • a seizure (convulsions); or
  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Serious side effects may be more likely in older adults.

Common side effects may include:

  • headache, muscle cramps;
  • dizziness, drowsiness;
  • confusion, depressed mood;
  • blurred vision;
  • diarrhea; or
  • pain, stinging, burning, redness, or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tigan Injection (Trimethobenzamide Hydrochloride Injectable)


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Tigan Injection Professional Information


There have been reports of hypersensitivity reactions and Parkinson-like symptoms. There have been instances of hypotension reported following parenteral administration to surgical patients. There have been reports of blood dyscrasias, blurring of vision, coma, convulsions, depression of mood, diarrhea, disorientation, dizziness, drowsiness, headache, jaundice, muscle cramps and opisthotonos. If these occur, the administration of the drug should be discontinued. Allergic-type skin reactions have been observed; therefore, the drug should be discontinued at the first sign of sensitization. While these symptoms will usually disappear spontaneously, symptomatic treatment may be indicated in some cases.

For medical advice about adverse reactions contact your medical professional. To report SUSPECTED ADVERSE REACTIONS, contact Par Pharmaceutical, Inc. at 1-800-828-9393 or FDA at 1-800-FDA-1088 (1-800-332-1088) or www.fda.gov/medwatch.

Read the entire FDA prescribing information for Tigan Injection (Trimethobenzamide Hydrochloride Injectable)

© Tigan Injection Patient Information is supplied by Cerner Multum, Inc. and Tigan Injection Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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