Medical Editor: John P. Cunha, DO, FACOEP
Timoptic 0.25% and 0.5% (timolol maleate) Ophthalmic Solution in Ocudose Dispenser is a beta-blocker used to treat open-angle glaucoma and other causes of high pressure inside the eye. Common side effects of Timoptic 0.25% and 0.5% Ophthalmic Solution in Ocudose include:
- burning and stinging when the drops are applied
- blurred vision
- double vision
- drooping eyelid
- burning or stinging in your eye
- tingling or cold feeling in your hands or feet
- ringing in your ears
- dry mouth
- loss of appetite
- upset stomach
- skin rash or worsening psoriasis
- sleep problems (insomnia)
- cough, or
- stuffy nose
Timoptic in Ocudose is available in concentrations of 0.25 and 0.5 %. The usual starting dose is one drop of 0.25 % Timoptic in Ocudose in the affected eye(s) administered twice a day. Timoptic may interact with clonidine, quinidine, reserpine, digitalis, acetazolamide, dichlorphenamide, methazolamide, oral timolol, other beta-blockers, calcium channel blockers, or antidepressants. Tell your doctor all medications and supplements you use. During pregnancy, Timoptic should be used only if prescribed. Timoptic passes into breast milk and could harm a nursing baby. Consult your doctor before breastfeeding.
Our Timoptic 0.25% and 0.5% (timolol maleate) Ophthalmic Solution in Ocudose Dispenser Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- swelling or redness of your eyelids;
- eye redness, discomfort, or sensitivity to light;
- drainage, crusting, or oozing of your eyes or eyelids;
- depressed mood, confusion, hallucinations, unusual thoughts or behavior;
- wheezing, gasping, or other breathing problems;
- swelling, rapid weight gain;
- chest pain, slow or uneven heart rate; or
- feeling short of breath, even with mild exertion.
Less serious side effects may include:
- blurred vision, double vision, drooping eyelid;
- burning or stinging in your eye;
- headache, weakness, drowsiness;
- numbness, tingling, or cold feeling in your hands or feet;
- ringing in your ears;
- dry mouth;
- nausea, diarrhea, loss of appetite, upset stomach;
- skin rash or worsening psoriasis;
- sleep problems (insomnia); or
- cough, stuffy nose.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Timoptic in Ocudose (Timolol Maleate Ophthalmic Solution)
The most frequently reported adverse experiences have been burning and stinging upon instillation (approximately one in eight patients).
The following additional adverse experiences have been reported less frequently with ocular administration of this or other timolol maleate formulations:
Body As A Whole
Headache, asthenia/fatigue, and chest pain.
Bradycardia, arrhythmia, hypotension, hypertension, syncope, heart block, cerebral vascular accident, cerebral ischemia, cardiac failure, worsening of angina pectoris, palpitation, cardiac arrest, pulmonary edema, edema, claudication, Raynaud's phenomenon, and cold hands and feet.
Dizziness, increase in signs and symptoms of myasthenia gravis, paresthesia, somnolence, insomnia, nightmares, behavioral changes and psychic disturbances including depression, confusion, hallucinations, anxiety, disorientation, nervousness, and memory loss.
Signs and symptoms of ocular irritation including conjunctivitis, blepharitis, keratitis, ocular pain, discharge (e.g., crusting), foreign body sensation, itching and tearing, and dry eyes; ptosis; decreased corneal sensitivity; cystoid macular edema; visual disturbances including refractive changes and diplopia; pseudopemphigoid; choroidal detachment following filtration surgery (see PRECAUTIONS, General); and tinnitus.
The following additional adverse effects have been reported in clinical experience with ORAL timolol maleate or other ORAL beta blocking agents, and may be considered potential effects of ophthalmic timolol maleate: Allergic: Erythematous rash, fever combined with aching and sore throat, laryngospasm with respiratory distress; Body as a Whole: Extremity pain, decreased exercise tolerance, weight loss; Cardiovascular: Worsening of arterial insufficiency, vasodilatation; Digestive: Gastrointestinal pain, hepatomegaly, vomiting, mesenteric arterial thrombosis, ischemic colitis; Hematologic: Nonthrombocytopenic purpura; thrombocytopenic purpura; agranulocytosis; Endocrine: Hyperglycemia, hypoglycemia; Skin: Pruritus, skin irritation, increased pigmentation, sweating; Musculoskeletal: Arthralgia; Nervous System/Psychiatric: Vertigo, local weakness, diminished concentration, reversible mental depression progressing to catatonia, an acute reversible syndrome characterized by disorientation for time and place, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics; Respiratory: Rales, bronchial obstruction; Urogenital: Urination difficulties.
Read the entire FDA prescribing information for Timoptic in Ocudose (Timolol Maleate Ophthalmic Solution)
© Timoptic in Ocudose Patient Information is supplied by Cerner Multum, Inc. and Timoptic in Ocudose Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.