Medical Editor: John P. Cunha, DO, FACOEP
Timoptic (timolol ophthalmic solution) is a beta-blocker drug that also reduces pressure inside the eye. Timoptic is used to treat open-angle glaucoma and other causes of high pressure inside the eye. Side effects of Timoptic include:
- blurred vision,
- double vision,
- drooping eyelid,
- burning or stinging in your eye,
- eye itching or redness,
- watery eyes,
- feeling as if something is in the eye,
- cold feeling in your hands or feet,
- ringing in your ears,
- dry mouth,
- loss of appetite,
- upset stomach,
- skin rash or worsening psoriasis,
- sleep problems (insomnia),
- cough, or
- stuffy nose.
Tell your doctor if you have unlikely but serious side effects of Timoptic including:
- eye pain/swelling/discharge,
- slow or irregular heartbeat,
- muscle weakness,
- mental/mood changes, or
- coldness/numbness/pain in the hands or feet.
The usual starting dose of Timoptic is one drop of 0.25 percent in the affected eye(s) twice a day. Timoptic may interact with oral beta-blockers, calcium antagonists, catecholamine-depleting drugs, digitalis, quinidine, SSRI antidepressants, clonidine, and injectable epinephrine. Tell your doctor all medications and supplements you use. It is not known whether timolol ophthalmic is harmful to an unborn baby, so Timoptic should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Timolol ophthalmic is excreted into human breast milk. Because of the potential for serious adverse reactions from TIMOPTIC in nursing infants, a decision should be made whether to discontinue breastfeeding or to discontinue the drug.
Our Timoptic Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- swelling or redness of your eyelids;
- eye redness, discomfort, or sensitivity to light;
- drainage, crusting, or oozing of your eyes or eyelids;
- depressed mood, confusion, hallucinations, unusual thoughts or behavior;
- wheezing, gasping, or other breathing problems;
- swelling, rapid weight gain;
- chest pain, slow or uneven heart rate; or
- feeling short of breath, even with mild exertion.
Less serious side effects may include:
- blurred vision, double vision, drooping eyelid;
- burning or stinging in your eye;
- headache, weakness, drowsiness;
- numbness, tingling, or cold feeling in your hands or feet;
- ringing in your ears;
- dry mouth;
- nausea, diarrhea, loss of appetite, upset stomach;
- skin rash or worsening psoriasis;
- sleep problems (insomnia); or
- cough, stuffy nose.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Timoptic (Timolol Maleate Ophthalmic Solution)
The most frequently reported adverse experiences have been burning and stinging upon instillation (approximately one in eight patients).
The following additional adverse experiences have been reported less frequently with ocular administration of this or other timolol maleate formulations:
Body As A Whole
Headache, asthenia/fatigue, and chest pain.
Bradycardia, arrhythmia, hypotension, hypertension, syncope, heart block, cerebral vascular accident, cerebral ischemia, cardiac failure, worsening of angina pectoris, palpitation, cardiac arrest, pulmonary edema, edema, claudication, Raynaud's phenomenon, and cold hands and feet.
Dizziness, increase in signs and symptoms of myasthenia gravis, paresthesia, somnolence, insomnia, nightmares, behavioral changes and psychic disturbances including depression, confusion, hallucinations, anxiety, disorientation, nervousness, and memory loss.
Signs and symptoms of ocular irritation including conjunctivitis, blepharitis, keratitis, ocular pain, discharge (e.g., crusting), foreign body sensation, itching and tearing, and dry eyes; ptosis; decreased corneal sensitivity; cystoid macular edema; visual disturbances including refractive changes and diplopia; pseudopemphigoid; choroidal detachment following filtration surgery [see PRECAUTIONS, General]; and tinnitus.
The following additional adverse effects have been reported in clinical experience with ORAL timolol maleate or other ORAL beta-blocking agents and may be considered potential effects of ophthalmic timolol maleate: Allergic: Erythematous rash, fever combined with aching and sore throat, laryngospasm with respiratory distress; Body as a Whole: Extremity pain, decreased exercise tolerance, weight loss; Cardiovascular: Worsening of arterial insufficiency, vasodilatation; Digestive: Gastrointestinal pain, hepatomegaly, vomiting, mesenteric arterial thrombosis, ischemic colitis; Hematologic: Nonthrombocytopenic purpura; thrombocytopenic purpura, agranulocytosis; Endocrine: Hyperglycemia, hypoglycemia; Skin: Pruritus, skin irritation, increased pigmentation, sweating; Musculoskeletal: Arthralgia; Nervous System/Psychiatric: Vertigo, local weakness, diminished concentration, reversible mental depression progressing to catatonia, an acute reversible syndrome characterized by disorientation for time and place, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics; Respiratory: Rales, bronchial obstruction; Urogenital: Urination difficulties.
Read the entire FDA prescribing information for Timoptic (Timolol Maleate Ophthalmic Solution)
© Timoptic Patient Information is supplied by Cerner Multum, Inc. and Timoptic Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.