Tirosint Side Effects Center

Last updated on RxList: 3/31/2022
Tirosint Side Effects Center

What Is Tirosint?

Tirosint (levothyroxine sodium) is a replacement for a hormone that is normally produced by your thyroid gland to regulate the body's energy and metabolism used to treat hypothyroidism (low thyroid hormone). Tirosint is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer. Tirosint is available in generic form.

What Are Side Effects of Tirosint?

Common side effects of Tirosint include hair loss, changes in menstrual cycle, and appetite or weight changes. Tell your doctor if you have a serious side effect of Tirosint including headache, sleep problems (insomnia), nervous feeling, irritability, fever, hot flashes, sweating, pounding heartbeats, or fluttering in your chest.

Dosage for Tirosint

Tirosint is taken in a single daily dose, ranging in strengths of 13 mcg to 150 mcg, preferably ½ to 1 hour before breakfast.

What Drugs, Substances, or Supplements Interact with Tirosint?

Tirosint may interact with medications such as calcium carbonate (Caltrate, Citracal, Oystercal, and others), iron supplements, sucralfate (Carafate), sodium polystyrene sulfonate (Kayexalate, Kionex, and others), antacids containing aluminum (Maalox, Mylanta, Tums, and others), and cholesterol-lowering drugs cholestyramine (Questran) and colestipol (Colestid). Tell your doctor all medications or supplements you take.

Tirosint During Pregnancy and Breastfeeding

If you are pregnant or become pregnant, tell your doctor because your dose may need adjustment. This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

Additional Information

Our Tirosint (levothyroxine sodium) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Hyperthyroidism Symptoms and Treatment See Slideshow
Tirosint Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fast or irregular heartbeats;
  • chest pain, pain spreading to your jaw or shoulder;
  • shortness of breath;
  • fever, hot flashes, sweating;
  • tremors, or if you feel unusually cold;
  • weakness, tiredness, sleep problems (insomnia);
  • memory problems, feeling depressed or irritable;
  • headache, leg cramps, muscle aches;
  • feeling nervous or irritable;
  • dryness of your skin or hair, hair loss;
  • irregular menstrual periods; or
  • vomiting, diarrhea, appetite changes, weight changes.

Certain side effects may be more likely in older adults.

Common side effects may include:

  • chest pain, irregular heartbeats;
  • shortness of breath;
  • headache, leg cramps, muscle pain or weakness;
  • tremors, feeling nervous or irritable, trouble sleeping;
  • increased appetite;
  • feeling hot;
  • weight loss;
  • changes in your menstrual periods;
  • diarrhea; or
  • skin rash, partial hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tirosint (Levothyroxine Sodium Capsules)

QUESTION

Where is the thyroid gland located? See Answer
Tirosint Professional Information

SIDE EFFECTS

Adverse reactions associated with TIROSINT therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see WARNINGS AND PRECAUTIONS and OVERDOSAGE]. They include the following:

Seizures have been reported rarely with the institution of levothyroxine therapy.

Adverse Reactions In Children

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height.

Hypersensitivity Reactions

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various GI symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.

Read the entire FDA prescribing information for Tirosint (Levothyroxine Sodium Capsules)

© Tirosint Patient Information is supplied by Cerner Multum, Inc. and Tirosint Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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