Tolsura vs. Lamisil

Are Tolsura and Lamisil the Same Thing?

Tolsura (itraconazole capsules) and Lamisil (terbinafine hydrochloride) are antifungals used to treat different types of infections.

Tolsura is used to treat blastomycosis, pulmonary and extrapulmonary; histoplasmosis, including chronic cavitary pulmonary disease and disseminated, non-meningeal histoplasmosis; and aspergillosis, pulmonary and extrapulmonary, in patients who are intolerant of or who are refractory to amphotericin B therapy.

Lamisil is used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis). Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

Lamisil cream is available over-the-counter (OTC) and as a generic.

Side effects of Tolsura and Lamisil that are similar include nausea, abdominal or stomach pain, skin rash, headache, diarrhea, itching, and dizziness.

Side effects of Tolsura that are different from Lamisil include vomiting, fluid retention (edema), fatigue, fever, high blood pressure (hypertension), abnormal liver function, low blood potassium, loss of appetite, feeling unwell (malaise), drowsiness, albuminuria, decreased sex drive, and impotence.

Side effects of Lamisil that are different from Tolsura include stomach upset, gas, spinning sensation, and temporary unusual or unpleasant taste or loss of taste in your mouth.

Both Tolsura and Lamisil may interact with other antifungals, blood thinners, heart rhythm medications, antidepressants, and beta-blockers.

Tolsura may also interact with alpha blockers, narcotics, antibiotics, antiplatelet drugs, anticonvulsants, diabetes drugs, antihelminthics, antiprotozoals, migraine headache medicines, cancer drugs, antipsychotics, anxiety drugs, hypnotics, antivirals, calcium channel blockers, heart medications, contraceptives, diuretics, gastrointestinal drugs, immunosuppressants, statins, urologic drugs, vasopressin receptor antagonists, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Lamisil may also interact with cimetidine, rifampin, and monoamine oxidase inhibitors (MAOIs).

What Are Possible Side Effects of Tolsura?

Common side effects of Tolsura include:

  • nausea,
  • rash,
  • vomiting,
  • fluid retention (edema),
  • headache,
  • diarrhea,
  • fatigue,
  • fever,
  • itching,
  • high blood pressure (hypertension),
  • abnormal liver function,
  • abdominal pain,
  • dizziness,
  • low blood potassium,
  • loss of appetite,
  • feeling unwell (malaise),
  • decreased sex drive,
  • drowsiness,
  • albuminuria, and
  • impotence.

What Are Possible Side Effects of Lamisil?

Common side effects of Lamisil include:

  • headache,
  • dizziness,
  • drowsiness,
  • stomach or abdominal pain,
  • upset stomach,
  • diarrhea,
  • heartburn,
  • loss of appetite, and
  • allergic reactions including skin inflammation, itching, rash, and unusual or unpleasant taste in your mouth.

What Is Tolsura?

Tolsura (itraconazole capsules) is an azole antifungal indicated for the treatment of the following fungal infections in immunocompromised and non-immunocompromised adult patient: blastomycosis, pulmonary and extrapulmonary; histoplasmosis, including chronic cavitary pulmonary disease and disseminated, non-meningeal histoplasmosis; and aspergillosis, pulmonary and extrapulmonary, in patients who are intolerant of or who are refractory to amphotericin B therapy.

What Is Lamisil?

Lamisil (terbinafine hydrochloride) is an antifungal antibiotic used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis). Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow

What Drugs Interact With Tolsura?

Tolsura may interact with alpha blockers, narcotic pain relievers, antiarrhythmics, antibiotics, Anticoagulants, antiplatelet drugs, anticonvulsants, diabetes drugs, antihelminthics, antifungals, antiprotozoals, migraine headache medicines, cancer drugs, antipsychotics, anxiety drugs, hypnotics, antivirals, beta blockers, calcium channel blockers, heart medications, contraceptives, diuretics, gastrointestinal drugs, immunosuppressants, statins, antidepressants, urologic drugs, vasopressin receptor antagonists, and nonsteroidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Tolsura; it is unknown how it would affect a fetus. Tolsura passes into breast milk but it is unknown how it would affect a nursing infant. Consult your doctor before breastfeeding.

What Drugs Interact With Lamisil?

Lamisil may interact with cimetidine, rifampin, other antifungal antibiotics, blood thinners, heart rhythm medications, antidepressants, MAO inhibitors (MAOIs), or beta-blockers. Tell your doctor all medications you use. During pregnancy, Lamisil should be used only when prescribed.

How Should Tolsura Be Taken?

The dose of Tolsura to treat blastomycosis and histoplasmosis is 130 mg to 260 mg daily. The dose of Tolsura to treat aspergillosis is 130 mg to 260 mg daily.

How Should Lamisil Be Taken?

To treat fingernail onychomycosis the dose of Lamisil is one 250 mg tablet once daily for 6 weeks. For toenail onychomycosis, take one 250 mg tablet once daily for 12 weeks.

QUESTION

Bowel regularity means a bowel movement every day. See Answer
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References
Mayne Pharma. Tolsura Product Information.

https://tolsura.com

GSK. Lamisil Product Information.

https://www.lamisilat.com

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