Toradol vs. Anaprox (Naproxen, Naprosyn)

Are Toradol and Anaprox (Naproxen, Naprosyn) the Same Thing?

Toradol (ketorolac tromethamine) and Anaprox (Naproxen, Naprosyn) DS (naproxen) are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation.

Toradol is used to treat moderately severe pain and inflammation, usually after surgery.

Anaprox (Naproxen, Naprosyn) DS is used for pain management for many diseases, arthritic diseases, and inflammatory diseases such as tendonitis, bursitis, and gout.

The brand name Toradol is no longer available in the U.S. Generic versions may be available.

Side effects of Toradol and Anaprox (Naproxen, Naprosyn) DS that are similar include headache, heartburn, upset stomach, nausea, diarrhea, stomach or abdominal pain, bloating, gas, constipation, dizziness, and ringing in the ears.

Side effects of Toradol that are different from Anaprox (Naproxen, Naprosyn) DS include vomiting, drowsiness, and sweating.

Side effects of Anaprox (Naproxen, Naprosyn) DS that are different from Toradol include nervousness, skin rash, blurred vision, and itching.

Both Toradol and Anaprox (Naproxen, Naprosyn) DS may interact with alcohol, antidepressants, blood thinners, lithium, methotrexate, diuretics (water pills), steroids, aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), seizure medications, and heart or blood pressure medications.

Toradol may also interact with thiothixene, alprazolam, muscle relaxers, and ACE inhibitors.

Anaprox (Naproxen, Naprosyn) DS may also interact with cholestyramine, cyclosporine, digoxin, pemetrexed, probenecid, and insulin or oral diabetes medicines.

What Are Possible Side Effects of Toradol?

Common side effects of Toradol include:

  • headache,
  • heartburn,
  • upset stomach,
  • nausea,
  • vomiting,
  • diarrhea,
  • stomach pain,
  • bloating,
  • gas,
  • constipation,
  • dizziness,
  • drowsiness,
  • sweating,
  • and ringing in the ears.

What Are Possible Side Effects of Anaprox (Naproxen, Naprosyn)?

Common side effects of Anaprox (Naproxen, Naprosyn) include:

  • heartburn,
  • stomach or abdominal pain,
  • upset stomach,
  • nausea,
  • diarrhea,
  • constipation,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • skin rash,
  • headache,
  • blurred vision,
  • ringing in your ears, and
  • itching.

What is Toradol?

Toradol (ketorolac tromethamine) is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat moderately severe pain and inflammation, usually after surgery. Toradol works by blocking the production of prostaglandins, compounds that cause pain, fever, and inflammation. The brand name Toradol is no longer available in the U.S. Generic versions may be available.

What is Anaprox (Naproxen, Naprosyn)?

Anaprox (Naproxen, Naprosyn) is a proprionic acid derivative and is considered a nonsteroidal anti-inflammatory drug (NSAID) and is used for pain management for many diseases, arthritic diseases, and inflammatory diseases such as tendonitis, bursitis, and gout.

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What Drugs Interact With Toradol?

Drug interactions may occur with lithium, ACE inhibitors, warfarin, and medications used to treat high uric acid levels. Warnings may apply to individuals who have ulcers, cardiovascular disease, kidney disease, and bleeding disorders. People who are taking aspirin or NSAIDs should not take Toradol because of the cumulative risk of inducing serious NSAID-related side effects.

What Drugs Interact With Anaprox (Naproxen, Naprosyn)?

Naprosyn may interact with antidepressants, blood thinners, lithium, methotrexate, diuretics (water pills), steroids, aspirin or other NSAIDs, or heart or blood pressure medications. Tell your doctor all medications and supplements you use. Naprosyn may cause premature closing of the ductus arteriosus in the fetus and does enter breast milk; avoidance of the drug in pregnant and breastfeeding women is suggested.

How Should Toradol Be Taken?

Toradol is available as a 10 mg tablet and a solution (30 mg per ml) for intravenous (IV) or intramuscular (IM) administration. Toradol solution is administered as a single 15- to 60-mg dose once every 6 hours not to exceed 60 or 120 mg a day. The recommended oral dose is one to two Toradol tablets initially followed by one tablet every 4-6 hours, not to exceed 40 mg daily. Toradol should not be used for more than 5 days.

How Should Anaprox (Naproxen, Naprosyn) Be Taken?

Naprosyn is available in several doses and drug configurations; Naprosyn tablets with strengths of 250, 375 and 500 mg and as an oral suspension containing 125 mg Naprosyn per 5 ml of liquid, EC-Naprosyn (delayed release to reduce gastric irritation) with strengths of 375 and 500 mg, Anaprox in 275 mg tablets, Anaprox DS in 550 mg tablets. Almost all Naprosyn drugs are recommended to be dosed twice per day (every 12 hours) with children's doses (strength in mg per Kg) based on the child's weight, also twice a day with a maximum dose of 15 mg per Kg per day. Individuals with renal problems should avoid taking Naprosyn.

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References
SOURCE:

DailyMed. Toradol Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019645s019lbl.pdf

FDA. Anaprox Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017581s113,018164s063,020067s020lbl.pdf

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