Tradjenta vs. Glucophage, Glumetza, Riomet

Tradjenta (linagliptin) and Glucophage, Glumetza, Riomet, Glumetza, and Riomet (metformin hydrochloride) are oral diabetes medicines used as adjuncts to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Side effects of Tradjenta and Glucophage, Glumetza, Riomet, Glumetza, and Riomet that are similar include muscle pain, headache.

Side effects of Tradjenta that are different from Glucophage, Glumetza, Riomet, Glumetza, and Riomet include stuffy nose, runny nose, sore throat, cough, weight gain, joint pain, back pain, or low blood sugar.

Side effects of Glucophage, Glumetza, Riomet, Glumetza, and Riomet that are different from Tradjenta include weakness, nausea, vomiting, diarrhea, gas, or stomach pain.

Both Tradjenta and Glucophage, Glumetza, Riomet, Glumetza, and Riomet may interact with quinidine and seizure medications.

Tradjenta may also interact with bosentan, dexamethasone, ketoconazole, verapamil, rifabutin, rifampin, rifapentine, St. John's wort, barbiturates, medication to treat HIV/AIDS, medicines to treat narcolepsy, medicines used to prevent organ transplant rejection, probenecid, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates (including Pepto-Bismol), sulfa drugs, monoamine oxidase inhibitors (MAOIs), beta-blockers, or other oral diabetes medications.

Glucophage, Glumetza, Riomet, Glumetza, and Riomet may also interact with furosemide, nifedipine, cimetidine, ranitidine, digoxin, morphine, procainamide, quinine, some antibiotics, isoniazid, diuretics (water pills), steroids, heart or blood pressure medications, niacin, phenothiazines, thyroid medicines, birth control pills and other hormones, and diet pills or medicines to treat asthma, colds or allergies.

Common side effects of Tradjenta include:

• stuffy nose,
• runny nose,
• sore throat,
• cough,
• weight gain,
• muscle or joint pain,
• headache,
• back pain, or
• low blood sugar.

Tradjenta may cause serious side effects, including:

• inflammation of the pancreas (pancreatitis, symptoms include severe pain in your upper stomach spreading to your back, nausea and vomiting,
• loss of appetite,
• fast heart rate),
• fever, and headache with a severe blistering, peeling, and red skin rash.

Common side effects of Glucophage, Glumetza, Riomet include:

• headache,
• muscle pain,
• weakness,
• nausea,
• vomiting,
• diarrhea,
• gas, or
• stomach pain.

Contact your doctor if you experience serious side effects of Glucophage including shortness of breath, swelling or rapid weight gain, fever or chills, flu symptoms, body aches, muscle pain or weakness, numb or cold feeling in your arms or legs, trouble breathing, dizziness, or slow or irregular heart rate.

Tradjenta (linagliptin) tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Glucophage, Glumetza, Riomet (saxagliptin) are oral antihyperglycemic drugs used to treat type 2 diabetes.

Tradjenta may interact with bosentan, dexamethasone, ketoconazole, quinidine, verapamil, rifabutin, rifampin, rifapentine, St. John's wort, phenobarbital and other barbiturates, medication to treat HIV or AIDS, medicines to treat narcolepsy, medicines used to prevent organ transplant rejection, seizure medications, probenecid, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates (including Pepto-Bismol), sulfa drugs, monoamine oxidase inhibitors (MAOIs), beta-blockers, or other oral diabetes medications. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Tradjenta; it is not expected to harm an unborn baby. It is unknown if Tradjenta passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Glucophage, Glumetza, Riomet may interact with furosemide, nifedipine, cimetidine, ranitidine, amiloride, triamterene, digoxin, morphine, procainamide, quinidine, quinine, trimethoprim, vancomycin, isoniazid, diuretics (water pills), steroids, heart or blood pressure medications, niacins, phenothiazines, thyroid medicines, birth control pills and other hormones, seizure medicines, and diet pills or medicines to treat asthma, colds or allergies. Tell your doctor all medications and supplements you use.

The recommended dose of Tradjenta is 5 mg once daily.

Glucophage, Glumetza, Riomet should be given in divided doses with meals while Glucophage XR should generally be given once daily with the evening meal.