Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Tralement

Last reviewed on RxList: 7/20/2020
Tralement Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Tralement?

Tralement (trace elements injection 4) is a combination of trace elements (zinc sulfate, cupric sulfate, manganese sulfate and selenious acid) indicated in adult and pediatric patients weighing at least 10 kg as a source of zinc, copper, manganese, and selenium for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.

What Are Side Effects of Tralement?

Side effects of Tralement include:

  • adverse reactions with other components of parenteral nutrition solutions (pulmonary embolism due to pulmonary vascular precipitates, vein damage and thrombosis, aluminum toxicity) and
  • adverse reactions with the use of trace elements administered parenterally or by other routes of administration (neurologic toxicity with manganese, hepatic accumulation of copper and manganese, and hypersensitivity reactions with zinc and copper).

Dosage for Tralement

Each mL of Tralement provides zinc 3 mg, copper 0.3 mg, manganese 55 mcg, and selenium 60 mcg. (2.5) The recommended dosage of Tralement in adults and pediatric patients weighing at least 50 kg is 1 mL per day added to parenteral nutrition. Tralement is not recommended for patients who may require a lower dosage of one or more of the individual trace elements. The recommended dosage of Tralement in pediatric patients weighing 10 kg to 49 k is based on body weight and is 0.2 mL to 0.8 mL per day added to parenteral nutrition.

Tralement In Children

Tralement is approved for use in pediatric patients weighing at least 10 kg as a source of zinc, copper, manganese, and selenium for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. Safety and dosing recommendations in pediatric patients are based on published literature describing controlled studies of products containing zinc, copper, manganese, and selenium.

Tralement is not approved for use in pediatric patients weighing less than 10 kg because the product does not provide an adequate dosage of zinc, copper, or selenium to meet the needs of this subpopulation and exceeds the recommended dosage of manganese.

What Drugs, Substances, or Supplements Interact with Tralement?

Tralement may interact with other medicines.

Tell your doctor all medications and supplements you use.

Tralement During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Tralement; administration of the recommended dose of Tralement in parenteral nutrition is not expected to cause major birth defects, miscarriage, or adverse maternal or fetal outcomes. Deficiency of trace elements may result in adverse pregnancy and fetal outcomes. Zinc, copper, manganese, and selenium are present in human milk. Administration of the approved recommended dose of Tralement in parenteral nutrition is not expected to cause harm to a breastfed infant. Consult your doctor before breastfeeding.

Additional Information

Our Tralement (trace elements injection 4), for Intravenous Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

According to the USDA, there is no difference between a “portion” and a “serving.” See Answer
Tralement Professional Information

SIDE EFFECTS

The following adverse reactions were identified in clinical studies or post-marketing reports. Given that some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Adverse Reactions With Other Components Of Parenteral Nutrition Solutions

  • Pulmonary embolism due to pulmonary vascular precipitates [see WARNINGS AND PRECAUTIONS]
  • Vein damage and thrombosis [see WARNINGS AND PRECAUTIONS]
  • Aluminum toxicity [see WARNINGS AND PRECAUTIONS]

Adverse Reactions With The Use Of Trace Elements Administered Parenterally Or By Other Routes Of Administration

  • Neurologic toxicity with manganese [see WARNINGS AND PRECAUTIONS]
  • Hepatic accumulation of copper and manganese [see WARNINGS AND PRECAUTIONS]
  • Hypersensitivity reactions with zinc and copper [see WARNINGS AND PRECAUTIONS]

Read the entire FDA prescribing information for Tralement (Trace Elements)

SLIDESHOW

Heart Healthy Diet: 25 Foods You Should Eat See Slideshow
Related Resources for Tralement

© Tralement Patient Information is supplied by Cerner Multum, Inc. and Tralement Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors

CONTINUE SCROLLING FOR RELATED SLIDESHOW