Definition of Transthyretin

Reviewed on 6/3/2021

Transthyretin: A plasma protein consisting of 127 amino acids that binds retinol and thyroxine. The gene TTR that encodes transthyretin is in chromosome region 18q11.2-q12.1. Many distinct forms of amyloidosis have been related to different point mutations in TTR. Transthyretin is also called prealbumin (because it migrates faster than albumin in an acidic starch gel).


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