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Last reviewed on RxList: 7/18/2017
Tranxene Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 7/18/2017

Tranxene (clorazepate dipotassium) is a benzodiazepine used to treat anxiety, seizure disorders, and alcohol withdrawal symptoms. Tranxene is available in a generic form. Common side effects of Tranxene include:

  • dizziness,
  • drowsiness,
  • tiredness,
  • fatigue,
  • blurred vision,
  • sleep problems (insomnia),
  • nausea,
  • vomiting,
  • stomach pain,
  • upset stomach,
  • constipation,
  • dry mouth,
  • headache,
  • amnesia or forgetfulness,
  • muscle weakness,
  • lack of balance or coordination,
  • nervousness,
  • irritability, or
  • skin rash.

Serious side effects of Tranxene include:

  • confusion,
  • depression,
  • suicide ideation,
  • muscle tremors,
  • dependence and
  • urinary problems.

Tranxene (clorazepate dipotassium) is available in strengths of 3.75, 7.5 and 15 mg tablets. The starting dose is usually 30mg but may vary according to the type of problem treated; doctors should prescribe the dose. Tranxene may interact with alcohol, barbiturates, MAO inhibitors, medicines to treat psychiatric disorders, narcotics, or antidepressants. Tell your doctor all medications and supplements you use. Pregnant or breastfeeding women should either stop or do not start using Tranxene due to potential harm to the fetus or infant. The drug is not recommended for use in patients less than 9 years of age.

Our Tranxene Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tranxene Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • confusion, unusual thoughts or behavior;
  • depressed mood, thoughts of suicide or hurting yourself;
  • muscle twitching, tremor; or
  • problems with urination.

Less serious side effects may include:

  • drowsiness, tiredness;
  • amnesia or forgetfulness;
  • dizziness;
  • blurred vision;
  • feeling nervous or irritable;
  • sleep problems (insomnia);
  • muscle weakness, lack of balance or coordination;
  • skin rash;
  • nausea, vomiting, stomach pain, constipation; or
  • dry mouth; or
  • headache.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tranxene (Clorazepate Dipotassium)

Tranxene Professional Information


The side effect most frequently reported was drowsiness. Less commonly reported (in descending order of occurrence) were: dizziness, various gastrointestinal complaints, nervousness, blurred vision, dry mouth, headache, and mental confusion. Other side effects included insomnia, transient skin rashes, fatigue, ataxia, genitourinary complaints, irritability, diplopia, depression, tremor, and slurred speech.

There have been reports of abnormal liver and kidney function tests and of decrease in hematocrit.

Decrease in systolic blood pressure has been observed.

To report SUSPECTED ADVERSE REACTIONS, contact Recordati Rare Diseases Inc. at 1-888-575-8344 or FDA at 1-800-FDA-1088 or

Read the entire FDA prescribing information for Tranxene (Clorazepate Dipotassium)

Related Resources for Tranxene

Read the Tranxene User Reviews »

© Tranxene Patient Information is supplied by Cerner Multum, Inc. and Tranxene Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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