Tremfya vs. Humira

Are Tremfya and Humira the Same Thing?

Tremfya (guselkumab) injection and Humira (adalimumab) are different types of monoclonal antibodies used to treat plaque psoriasis.

Humira is also used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and to treat Crohn's disease after other drugs have been tried without successful treatment of symptoms.

Side effects of Tremfya and Humira that are similar include injection site reactions (redness, itching, pain, bruising, swelling, or bleeding) and headache.

Side effects of Tremfya that are different from Humira include upper respiratory infections, joint pain, diarrhea, gastroenteritis (nausea, vomiting, diarrhea, cramps, and fever), tinea infections (athlete's foot, ringworm, jock itch), and herpes simplex infections.

Side effects of Humira that are different from Tremfya include stuffy nose, sinus pain, and stomach pain.

Tremfya may interact with "live" vaccines and CYP450 substrates.

Humira may interact with other drugs.

What Are Possible Side Effects of Tremfya?

Common side effects of Tremfya include:

  • upper respiratory infections,
  • headache,
  • injection site reactions,
  • joint pain,
  • diarrhea,
  • gastroenteritis (nausea, vomiting, diarrhea, cramps, and fever),
  • tinea infections (athlete's foot, ringworm, jock itch), and
  • herpes simplex infections

What Are Possible Side Effects of Humira?

Common side effects of Humira include

  • injection site reactions (redness, itching, pain, bruising, swelling, or bleeding),
  • headache,
  • suffy nose,
  • sinus pain, or
  • stomach pain.

Tell your doctor if you have serious side effects of Humira including:

  • fast/irregular/pounding heartbeat,
  • stomach pain,
  • blood in the stools,
  • mental/mood changes,
  • severe headache,
  • easy bruising or bleeding,
  • dark urine,
  • yellowing eyes and skin,
  • leg pain or swelling,
  • numbness or tingling of the arms/hands/legs/feet,
  • unsteadiness,
  • unexplained muscle weakness,
  • difficulty with speaking/chewing/swallowing/facial movements,
  • vision changes,
  • extreme fatigue,
  • joint pain, or
  • butterfly-shaped rash on the nose and cheeks.

What Is Tremfya?

Tremfya (guselkumab) injection, for subcutaneous use is an interleukin-23 blocker indicated for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer

What Is Humira?

Humira (adalimumab) is an injectable protein (antibody) used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. Humira is also used to treat Crohn's disease after other drugs have been tried without successful treatment of symptoms.

What Drugs Interact With Tremfya?

Tremfya may interact with "live" vaccines and CYP450 substrates. Tell your doctor all medications and supplements you use and all vaccines you recently received. Tell your doctor if you are pregnant or plan to become pregnant before using Tremfya; it is unknown how it would affect a fetus. Human IgG antibodies are known to cross the placental barrier; therefore, Tremfya may be transmitted from the mother to the developing fetus. It is unknown if Tremfya passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Humira?

Other drugs may interact with Humira. Tell your doctor all prescription and over-the-counter medications and supplements you use.

How Should Tremfya be Taken?

The dose of Tremfya is 100 mg administered by subcutaneous injection at Week 0, Week 4 and every 8 weeks thereafter.

How Should Humira be Taken?

The recommended dose of Humira for adult patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), or ankylosing spondylitis (AS) is 40 mg administered every other week. Pediatric dosage is determined by the child's weight.

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow
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References
Janssen Biotech, Inc. Tremfya Product Information.

www.tremfya.com/

Abbvie. Humira Product Information.

www.humira.com/ ? ?

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