Tremfya vs. Stelara

Are Tremfya and Stelara the Same Thing?

Tremfya (guselkumab) injection and Stelara (ustekinumab) injection are monoclonal antibodies used to treat plaque psoriasis.

Side effects of Tremfya and Stelara that are similar include injection site reactions (bruising, itching, pain, redness, swelling, and hardening of the skin), headache, and diarrhea.

Side effects of Tremfya that are different from Stelara include upper respiratory infections, joint pain, gastroenteritis (nausea, vomiting, diarrhea, cramps, and fever), tinea infections (athlete's foot, ringworm, jock itch), and herpes simplex infections.

Side effects of Stelara that are different from Tremfya include cold symptoms (stuffy nose, sneezing, sore throat), tired feeling, and skin rash or itching.

Both Tremfya and Stelara may interact with "live" vaccines.

Tremfya may also interact with CYP450 substrates.

What Are Possible Side Effects of Tremfya?

Common side effects of Tremfya include:

  • upper respiratory infections,
  • headache,
  • injection site reactions,
  • joint pain,
  • diarrhea,
  • gastroenteritis (nausea, vomiting, diarrhea, cramps, and fever),
  • tinea infections (athlete's foot, ringworm, jock itch), and
  • herpes simplex infections

What Are Possible Side Effects of Stelara?

Common side effects of Stelara include

  • injection site reactions (bruising, itching, pain, redness, swelling, and hardening of the skin),
  • cold symptoms (stuffy nose, sneezing, sore throat),
  • headache,
  • tired feeling,
  • diarrhea, or
  • skin rash or itching.

Stelara can affect your immune system and can lower your body's ability to fight an infection. Tell your doctor if you develop signs of an infection, such as:

  • worsening redness/swelling/tenderness at the injection site after 2 days,
  • fever or chills,
  • cold or flu symptoms,
  • severe stomach pain, or
  • persistent nausea or vomiting.

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow

What Is Tremfya?

Tremfya (guselkumab) injection, for subcutaneous use is an interleukin-23 blocker indicated for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

What Is Stelara?

Stelara (ustekinumab) Injection is a monoclonal antibody used to treat plaque psoriasis.

What Drugs Interact With Tremfya?

Tremfya may interact with "live" vaccines and CYP450 substrates. Tell your doctor all medications and supplements you use and all vaccines you recently received. Tell your doctor if you are pregnant or plan to become pregnant before using Tremfya; it is unknown how it would affect a fetus. Human IgG antibodies are known to cross the placental barrier; therefore, Tremfya may be transmitted from the mother to the developing fetus. It is unknown if Tremfya passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Stelara?

Live vaccines such as the polio and flu vaccine may interact with Stelara. Tell your doctor all medications you use, all recent vaccines you have received, and all infections you have had. Stelara may weaken your body's ability to fight infections.

How Should Tremfya be Taken?

The dose of Tremfya is 100 mg administered by subcutaneous injection at Week 0, Week 4 and every 8 weeks thereafter.

How Should Stelara be Taken?

The recommended dosage of Stelara is either 45 mg or 90 mg given on day one, then 4 weeks later, and every 12 weeks thereafter.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
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References
Janssen Biotech, Inc. Tremfya Product Information.

www.tremfya.com/

Janssen Biotech, Inc. Skyrizi Product Information.

https://www.stelarainfo.com/crohns-disease/about-stelara#how-stelara-works ? ?

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