Tresiba vs. Myxredlin

Are Tresiba and Myxredlin the Same Thing?

Tresiba (insulin degludec injection) and Myxredlin (insulin human in sodium chloride injection) are forms of insulin indicated to improve glycemic control in adults with diabetes mellitus.

A difference is Tresiba is a long-acting human insulin and Myxredlin is a short-acting human insulin.

Myxredlin is also used in pediatric patients with diabetes mellitus.

Side effects of Tresiba and Myxredlin that are similar include low blood sugar (hypoglycemia), allergic reactions, and weight gain.

Side effects of Tresiba that are different from Myxredlin include injection site reactions, body fat redistribution, itching, rash, swelling, runny or stuffy nose, upper respiratory tract infection, headache, sinusitis, upset stomach or stomach pain, and diarrhea.

Side effects of Myxredlin that are different from Tresiba include fluid retention (edema).

Both Tresiba and Myxredlin may interact with other insulin products, other antidiabetics, beta-blockers, clonidine, guanethidine, reserpine, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs, sulfonamide antibiotics, atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic agents, thyroid hormones, alcohol, lithium salts, and pentamidine.

Tresiba may also interact with propoxyphene, GLP-1 receptor agonists, DDP-4 inhibitors, and SGLT-2 inhibitors.

What Are Possible Side Effects of Tresiba?

Common side effects of Tresiba include:

  • low blood sugar (hypoglycemia),
  • allergic reactions,
  • injection site reactions,
  • body fat redistribution (lipodystrophy),
  • itching,
  • rash,
  • swelling,
  • weight gain,
  • runny or stuffy nose,
  • upper respiratory tract infection,
  • headache,
  • sinusitis,
  • upset stomach or stomach pain, and
  • diarrhea.

What Are Possible Side Effects of Myxredlin?

Common side effects of Myxredlin include:

  • low blood sugar (hypoglycemia),
  • allergic reactions,
  • weight gain, and
  • fluid retention (edema)

What Is Tresiba?

Tresiba (insulin degludec injection) is a long-acting human insulin analog indicated to improve glycemic control in adults with diabetes mellitus.

What Is Myxredlin?

Myxredlin (insulin human in sodium chloride injection) is a short-acting human insulin indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus.

QUESTION

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What Drugs Interact With Tresiba?

Tresiba may interact with other insulin products, beta-blockers, clonidine, guanethidine, reserpine, other antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs, sulfonamide antibiotics, GLP-1 receptor agonists, DDP-4 inhibitors, SGLT-2 inhibitors, atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic agents, thyroid hormones, alcohol, lithium salts, or pentamidine. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while taking Tresiba. During pregnancy, Tresiba should only be taken if prescribed. It is unknown if Tresiba passes into breast milk. Women with diabetes who are nursing may require adjustments in insulin dose, meal plan, or both. Consult your doctor before breastfeeding.

What Drugs Interact With Myxredlin?

Myxredlin may interact with antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs, sulfonamide antibiotics, atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), thyroid hormones, alcohol, beta-blockers, lithium salts, and pentamidine, clonidine, guanethidine, and reserpine. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Myxredlin; it is not expected to harm a fetus. There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy. Myxredlin passes into breast milk. Consult your doctor before breastfeeding.

How Should Tresiba Be Taken?

The dose of Tresiba is individualized based on type of diabetes, metabolic needs, blood glucose monitoring results, and glycemic control goal.

How Should Myxredlin Be Taken?

The dose of Myxredlin is individualized based on metabolic needs, blood glucose monitoring results, and glycemic control goal.

SLIDESHOW

Type 1 Diabetes: What Are The Symptoms? See Slideshow
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References


Novo Nordisk. Tresiba Product Information.

https://www.tresibapro.com

FDA. Myxredlin Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/208157s000lbl.pdf

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