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Trintellix vs. Prozac

Are Trintellix and Prozac the Same Thing?

Trintellix (vortioxetine) and Prozac (fluoxetine) are selective serotonin reuptake inhibitor (SSRI) type antidepressants used to treat major depressive disorder (MDD).

Prozac is also used to treat bulimia, obsessive-compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder (PMDD).

What Are Possible Side Effects of Trintellix?

Common side effects of Trintellix include:

  • nausea
  • diarrhea
  • dry mouth
  • constipation
  • vomiting
  • gas
  • dizziness
  • abnormal dreams
  • itching, and
  • decreased sexual desire

Antidepressants such as Trintellix increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. Tell your doctor if you experience any thoughts of suicide while taking Trintellix.

What Are Possible Side Effects of Prozac?

Common side effects of Prozac include:

  • nausea,
  • upset stomach,
  • constipation,
  • headaches,
  • anxiety,
  • sleep problems (insomnia),
  • drowsiness,
  • dizziness,
  • nervousness,
  • heart palpitations,
  • loss of appetite or increase in appetite,
  • weight changes,
  • cold symptoms (stuffy nose, sneezing, sore throat),
  • dry mouth,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

What is Trintellix?

Trintellix (vortioxetine) tablets are an antidepressant indicated for the treatment of major depressive disorder (MDD).

What is Prozac?

Prozac is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of nottreating it. You should discuss all treatment choices with your healthcare provider.

Prozac is used to treat:

  • Major Depressive Disorder (MDD)
  • Obsessive Compulsive Disorder (OCD)
  • Bulimia Nervosa*
  • Panic Disorder*
  • Depressive episodes associated with Bipolar I Disorder, taken with olanzapine (Zyprexa)
  • Treatment Resistant Depression (depression that has not gotten better with atleast 2 other treatments), taken with olanzapine (Zyprexa)*

*Not approved for use in children

Talk to your healthcare provider if you do not think that your condition is getting betterwith Prozac treatment.

What Drugs Interact With Trintellix?

Trintellix may interact with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans, buspirone, tramadol, tryptophan products, NSAIDs, aspirin, warfarin, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, and phenytoin. Tell your doctor all medications and supplements you use.

What Drugs Interact With Prozac?

Prozac may interact with cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, medicine for seizures or anxiety, monoamine oxidase inhibitors (MAOIs), nonsteroidal anti-inflammatory drugs (NSAIDs), other antidepressants, blood thinners, or migraine headache medicines.

Prozac may also interact with alprazolam, clopidogrel, clozapine, flecainide, haloperidol, nebivolol, vinblastine, or seizure medications.

Withdrawal symptoms may occur if you suddenly stop taking Prozac.

How Should Trintellix Be Taken?

The recommended starting dose of Trintellix is 10 mg administered orally once daily without regard to meals. Dosage should then be increased to 20 mg/day, as tolerated.

How Should Prozac Be Taken?

Take Prozac exactly as prescribed. Your healthcare provider may need to change the dose of Prozac until it is the right dose for you.

Prozac may be taken with or without food.

If you miss a dose of Prozac, take the missed dose as soon as you remember.If it is almost time for the next dose, skip the missed dose and take your nextdose at the regular time. Do not take two doses of Prozac at the same time.

If you take too much Prozac, call your healthcare provider or poison controlcenter right away, or get emergency treatment.

Reviewed on 10/10/2018

References:
Takeda Pharmaceuticals U.S.A., Inc. Trintellix Product Information
https://us.trintellix.com
DailyMed. Prozac Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c88f33ed-6dfb-4c5e-bc01-d8e36dd97299

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