Medical Editor: John P. Cunha, DO, FACOEP
Triostat (liothyronine sodium injection) (T3) is a thyroid hormone preparation indicated in the treatment of myxedema coma/precoma. Triostat can be used in patients allergic to desiccated thyroid or thyroid extract derived from pork or beef. Triostat is available in generic form. Common side effects of Triostat include:
- abnormal heart rhythm
- fast heart rate
- cardiac arrest
- low blood pressure
- heart attack
- chest pain (angina)
- congestive heart failure
- high blood pressure
- inflammation of veins (phlebitis)
An initial intravenous Triostat dose ranging from 25 mcg to 50 mcg is recommended in the emergency treatment of myxedema coma/precoma in adults. Triostat may interact with oral anticoagulants, insulin or oral hypoglycemics, estrogen, oral contraceptives, tricyclic antidepressants, digitalis, ketamine, and vasopressors. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant before receiving Triostat. Thyroid hormones do not readily cross the placental barrier and in general, thyroid replacement therapy to hypothyroid women should not be discontinued during pregnancy. Minimal amounts of Triostat pass into breast milk. Thyroid hormones such as Triostat are not generally associated with serious side effects. Consult your doctor before breastfeeding.
Our Triostat (liothyronine sodium injection) (T3) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
The most frequently reported adverse events were arrhythmia (6% of patients) and tachycardia (3%). Cardiopulmonary arrest, hypotension and myocardial infarction occurred in approximately 2% of patients. The following events occurred in approximately 1% or fewer of patients: angina, congestive heart failure, fever, hypertension, phlebitis and twitching.
In rare instances, allergic skin reactions have been reported with liothyronine sodium tablets.
For medical advice about your adverse reactions contact your medical professional. To report SUSPECTED ADVERSE REACTIONS, contact JHP at 1-866-923-2547 or MEDWATCH at 1-800-FDA-1088 (1-800-332-1088) or http://www.fda.gov/medwatch/.
Read the entire FDA prescribing information for Triostat (Liothyronine Sodium Injection)