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Trivaris

Last reviewed on RxList: 2/14/2018
Trivaris Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/14/2018

Trivaris (triamcinolone acetonide injectable suspension) is a steroid that is injected into the joint space to treat inflammation of the joints or tendons to treat arthritis, bursitis, or epicondylitis (tennis elbow). Trivaris is usually given in these conditions only as a short-term treatment of a severe or aggravated episode. Trivaris is also injected into soft tissues of the body to treat certain skin disorders caused by autoimmune conditions such as lupus, psoriasis, lichen planus, and others. The brand name Trivaris is discontinued, but generic versions may be available. Common side effects of Trivaris (triamcinolone acetonide injectable suspension) include:

  • nausea
  • bloating
  • appetite changes
  • stomach or side pain
  • headache
  • sleep problems (insomnia)
  • acne
  • skin scaling
  • other skin changes,
  • a wound that is slow to heal
  • thinning hair
  • bruising or swelling
  • sweating more than usual, or
  • irregular menstrual periods

The initial dose of Trivaris 80 mg/mL may vary from 2.5 mg to 100 mg per day depending on the specific disease entity being treated. Trivaris may interact with birth control pills or hormone replacement therapy, blood thinners, cyclosporine, digoxin, insulin or oral diabetes medications, isoniazid, rifampin, seizure medications, antibiotics, or aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications and supplements you use. It is unknown if Trivaris injection will harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. This drug can pass into breast milk and may harm a nursing baby. You should not breastfeed while you are using Trivaris injection.

Our Trivaris (triamcinolone acetonide injectable suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Trivaris Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • (after injection into a joint space) increased pain or swelling, joint stiffness, fever, and general ill feeling;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • unusual changes in mood or behavior;
  • swelling, rapid weight gain, feeling short of breath;
  • stomach cramps, vomiting, diarrhea, bloody or tarry stools, rectal irritation;
  • sudden numbness or weakness (especially on one side of the body);
  • a seizure (convulsions);
  • severe headache, blurred vision, pounding in your neck or ears;
  • increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or
  • signs of low adrenal gland hormones--flu-like symptoms, headache, depression, weakness, tiredness, diarrhea, vomiting, stomach pain, craving salty foods, and feeling light-headed.

Certain side effects may be more likely with long-term use or repeated doses of triamcinolone injection.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • skin changes (acne, dryness, redness, bruising, discoloration);
  • increased hair growth, or thinning hair;
  • nausea, bloating, appetite changes;
  • stomach or side pain;
  • cough, runny or stuffy nose;
  • headache, sleep problems (insomnia);
  • a wound that is slow to heal;
  • sweating more than usual; or
  • changes in your menstrual periods.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Trivaris (Triamcinolone Acetonide Injectable Suspension)

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Trivaris Professional Information

SIDE EFFECTS

(listed alphabetically under each subsection)

The following adverse reactions may be associated with corticosteroid therapy:

Allergic Reactions

Anaphylactoid reaction, anaphylaxis, angioedema.

Cardiovascular

Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture following recent myocardial infarction (see WARNINGS AND PRECAUTIONS), pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis.

Dermatologic

Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scaly skin, ecchymoses and petechiae, edema, erythema, hyperpigmentation, hypopigmentation, impaired wound healing, increased sweating, lupus erythematosuslike lesions, purpura, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria.

Endocrine

Decreased carbohydrate and glucose tolerance, development of cushingoid state, glycosuria, hirsutism, hypertrichosis, increased requirements for insulin or oral hypoglycemic agents in diabetes, manifestations of latent diabetes mellitus, menstrual irregularities, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in pediatric patients.

Fluid and Electrolyte Disturbances

Congestive heart failure in susceptible patients, fluid retention, hypokalemic alkalosis, potassium loss, sodium retention.

Gastrointestinal

Abdominal distention, bowel/bladder dysfunction (after intrathecal administration), elevation in serum liver enzyme levels (usually reversible upon discontinuation), hepatomegaly, increased appetite, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, perforation of the small and large intestine (particularly in patients with inflammatory bowel disease), ulcerative esophagitis.

Metabolic

Negative nitrogen balance due to protein catabolism.

Musculoskeletal

Aseptic necrosis of femoral and humeral heads, calcinosis (following intra-articular or intralesional use), Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, post injection flare (following intra-articular use), steroid myopathy, tendon rupture, vertebral compression fractures.

Neurologic/Psychiatric

Convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudotumor cerebri) usually following discontinuation of treatment, insomnia, mood swings, neuritis, neuropathy, paresthesia, personality changes, psychic disorders, vertigo. Arachnoiditis, meningitis, paraparesis/paraplegia, and sensory disturbances have occurred after intrathecal administration

Ophthalmic

Abnormal sensation in eye, anterior chamber cells, anterior chamber flare, cataract, cataract cortical, cataract nuclear, cataract subcapsular, conjunctival haemorrhage, exophthalmos, eye irritation, eye pain, eye pruritus, foreign body sensation in eyes, glaucoma, intraocular pressure increased, injection site haemorrhage, lacrimation increased, vitreous detachment, vitreous floaters and rare instances of blindness associated with intravitreal or periocular injections.

Other

Abnormal fat deposits, decreased resistance to infection, hiccups, increased or decreased motility and number of spermatozoa, malaise, moon face, weight gain.

Read the entire FDA prescribing information for Trivaris (Triamcinolone Acetonide Injectable Suspension)

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© Trivaris Patient Information is supplied by Cerner Multum, Inc. and Trivaris Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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