Trulicity vs. Januvia

Are Trulicity and Januvia the Same Thing?

Trulicity (dulaglutide) and Januvia (sitagliptin) are diabetes medications used as adjuncts to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Trulicity and Januvia are different types of diabetes medications. Trulicity is a human GLP-1 receptor agonist and Januvia is a DPP-4 inhibitor.

Side effects of Trulicity and Januvia that are similar include nausea, abdominal or stomach pain or discomfort, diarrhea, constipation, and low blood sugar (hypoglycemia).

Side effects of Trulicity that are different from Januvia include vomiting, decreased appetite, indigestion, frequent bowel movements, fatigue, gas, bloating, gastroesophageal reflux disease (GERD), weakness/lack of energy, feeling unwell (malaise), and belching.

Side effects of Januvia that are different from Trulicity include runny or stuffy nose, sore throat, headache, back pain, and joint or muscle pain.

Trulicity may interact with other oral medications taken at the same time.

Januvia may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers.

What Are Possible Side Effects of Trulicity?

Common side effects of Trulicity include:

  • nausea,
  • diarrhea,
  • frequent bowel movements,
  • vomiting,
  • abdominal pain or discomfort,
  • decreased appetite,
  • indigestion,
  • fatigue,
  • constipation,
  • gas,
  • bloating,
  • gastroesophageal reflux disease (GERD),
  • weakness/lack of energy,
  • feeling unwell (malaise),
  • belching, and
  • low blood sugar (hypoglycemia).

What Are Possible Side Effects of Januvia?

Common side effects of Januvia include:

  • runny or stuffy nose,
  • sore throat,
  • headache,
  • back pain,
  • joint or muscle pain,
  • nausea,
  • stomach pain,
  • diarrhea, or
  • constipation.

Although Januvia by itself usually does not cause low blood sugar (hypoglycemia), low blood sugar may occur if Januvia is prescribed with other anti-diabetic medications. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet.

What Is Trulicity?

Trulicity (dulaglutide) is a human GLP-1 receptor agonist used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

What Is Januvia?

Januvia (sitagliptin) is an oral diabetes medicine for people with type 2 diabetes (non-insulin-dependent) diabetes. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Many people using Januvia do not have serious side effects.

SLIDESHOW

Type 2 Diabetes: Signs, Symptoms, Treatments See Slideshow

What Drugs Interact With Trulicity?

Trulicity may interact with other oral medications. Tell your doctor all medications and supplements you use. During pregnancy, Trulicity should be taken only if prescribed; it is unknown if it would affect a fetus. It is unknown if Trulicity passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Januvia?

Januvia may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy Januvia should be used only when prescribed. Pregnancy may cause or worsen diabetes. Your doctor may change your diabetes treatment during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Trulicity Be Taken?

The recommended initiating dose of Trulicity is 0.75 mg once weekly. The maximum recommended dose is 1.5 mg once weekly.

How Should Januvia Be Taken?

The recommended dose of Januvia is 100 mg once daily.

QUESTION

______________ is another term for type 2 diabetes. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
SOURCE:

Eli Lilly and Company. Trulicity Product Information.

https://www.trulicity.com/

Merck. Januvia Product Information.

https://www.januvia.com

Health Solutions From Our Sponsors