Medical Editor: John P. Cunha, DO, FACOEP
Tussionex (chlorpheniramine and hydrocodone) is a combination antihistamine/antitussive drug prescribed for symptomatically managing cold and allergy symptoms. Common side effects of Tussionex include:
- trouble concentrating,
- mood changes,
- blurred vision,
- loss of appetite,
- dry mouth or throat,
- itching or skin rash, and
- disturbed coordination.
Contact your doctor if you have serious side effects of Tussionex including:
- shallow breathing,
- chest tightness,
- painful or difficult urination,
- mental/mood changes (such as depression, agitation, confusion, hallucinations),
- stomach/abdominal pain,
- fast/slow/irregular heartbeat, or
- unusual behavior.
Tussionex usual dose is 5 ml twice a day. Tussionex may interact with other drugs that can cause sleepiness (narcotics, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety), any other cold or allergy medicines, atropine, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, glycopyrrolate, mepenzolate, bladder or urinary medications, irritable bowel medications, or MAO inhibitors. Tell your doctor all medications and supplements you use. Tussionex should not be used during pregnancy as it may cause adverse effects in the fetus unless the potential benefit outweighs the potential unknown risk to the fetus. Tussionex is secreted in human breast milk and may cause adverse effects in the new born. Consult your doctor before breastfeeding.
Our Tussionex Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- weak or shallow breathing;
- chest tightness;
- painful urination;
- urinating less than usual or not at all; or
- confusion, hallucinations, or unusual behavior.
Less serious side effects may include:
- dizziness, drowsiness, trouble concentrating;
- mood changes, anxiety;
- blurred vision;
- constipation, nausea, vomiting, loss of appetite;
- dry mouth or throat;
- sweating; or
- mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Tussionex (Hydrocodone and Chlorpheniramine)
Nausea and vomiting may occur; they are more frequent in ambulatory than in recumbent patients. Prolonged administration of TUSSIONEX Pennkinetic Extended-Release Suspension may produce constipation.
General Disorders And Administration Site Conditions
Nervous System Disorders
Renal And Urinary Disorders
Ureteral spasm, spasm of vesical sphincters, and urinary retention have been reported with opiates.
Respiratory, Thoracic And Mediastinal Disorders
TUSSIONEX Pennkinetic Extended-Release Suspension may produce dose-related respiratory depression by acting directly on brain stem respiratory centers (see OVERDOSE). Use of TUSSIONEX Pennkinetic Extended-Release Suspension in children less than 6 years of age has been associated with fatal respiratory depression. Overdose with TUSSIONEX Pennkinetic Extended- Release Suspension in children 6 years of age and older, in adolescents, and in adults has been associated with fatal respiratory depression.
Skin And Subcutaneous Tissue Disorders
Read the entire FDA prescribing information for Tussionex (Hydrocodone and Chlorpheniramine)
© Tussionex Patient Information is supplied by Cerner Multum, Inc. and Tussionex Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.