Ubrelvy vs. Imitrex

Reviewed on 12/9/2020

Are Ubrelvy and Imitrex the Same Thing?

Ubrelvy (ubrogepant) and Imitrex (sumatriptan) are used to treat migraine headaches.

Ubrelvy and Imitrex belong to different drug classes. Ubrelvy is a calcitonin gene-related peptide receptor antagonist and Imitrex is a selective serotonin receptor agonist.

Side effects of Ubrelvy and Imitrex that are similar include nausea and drowsiness.

Side effects of Ubrelvy that are different from Imitrex include dry mouth.

Side effects of Imitrex that are different from Ubrelvy include mild headache (not a migraine), pain or chest tightness, pressure or heavy feeling in any part of your body, weakness, feeling hot or cold, dizziness, spinning sensation (vertigo), vomiting, drooling, unusual taste in your mouth after using nasal spray, burning/numbness/pain/irritation in your nose or throat after using nasal spray, and flushing (warmth, redness, or tingling under the skin).

Ubrelvy may interact with ketoconazole, itraconazole, clarithromycin, verapamil, cyclosporine, ciprofloxacin, fluconazole, fluvoxamine, grapefruit juice, rifampin, phenytoin, barbiturates, St. John's wort, quinidine, carvedilol, eltrombopag, and curcumin.

Imitrex may interact with sibutramine, monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), and ergot-containing medications.

What Are Possible Side Effects of Ubrelvy?

Common side effects of Ubrelvy include:

  • nausea,
  • drowsiness, and
  • dry mouth

What Are Possible Side Effects of Imitrex?

Common side effects of Imitrex include:

  • mild headache (not a migraine),
  • pain or chest tightness,
  • pressure or heavy feeling in any part of your body,
  • weakness,
  • feeling hot or cold,
  • dizziness,
  • spinning sensation,
  • drowsiness,
  • nausea,
  • vomiting,
  • drooling,
  • unusual taste in your mouth after using nasal spray,
  • burning/numbness/pain/irritation in your nose or throat after using nasal spray, or
  • flushing (warmth, redness, or tingling under the skin).

SLIDESHOW

16 Surprising Headache Triggers and Tips for Pain Relief See Slideshow

What Is Ubrelvy?

Ubrelvy (ubrogepant) is a calcitonin gene-related peptide receptor antagonist used for the acute treatment of migraine with or without aura in adults.

What Is Imitrex?

Imitrex (sumatriptan) is a selective serotonin receptor agonist used in oral, intranasal or injectable dosage form to treat migraine headaches. Imitrex is available as a generic drug.

What Drugs Interact With Ubrelvy?

Ubrelvy may interact with other medicines such as:

  • ketoconazole,
  • itraconazole,
  • clarithromycin,
  • verapamil,
  • cyclosporine,
  • ciprofloxacin,
  • fluconazole,
  • fluvoxamine,
  • grapefruit juice,
  • rifampin,
  • phenytoin,
  • barbiturates,
  • St. John's wort,
  • quinidine,
  • carvedilol,
  • eltrombopag, and
  • curcumin

Tell your doctor all medications and supplements you use.

What Drugs Interact With Imitrex?

Imitrex may interact with sibutramine (Meridia); monoamine oxidase inhibitors (MAOIs) isocarboxazid (Marplan); selective serotonin reuptake inhibitors, fluoxetine (Prozac) and sertraline (Zoloft), serotonin; norepinephrine reuptake inhibitors, venlafaxine (Effexor)) and duloxetine (Cymbalta); and ergot-containing medications, dihydroergotamine (Migranal) and ergotamine (Methergine).

How Should Ubrelvy be Taken?

The recommended dose of Ubrelvy is 50 mg or 100 mg taken orally, as needed. If needed, a second dose of Ubrelvy may be administered at least 2 hours after the initial dose.

How Should Imitrex be Taken?

The maximum single recommended adult dose of Imitrex Injection for the acute treatment of migraine or cluster headache is 6 mg injected subcutaneously. For the treatment of migraine, if side effects are dose limiting, lower doses (1 mg to 5 mg) of Imitrex may be used.

QUESTION

Who suffers more frequently from migraine headaches? See Answer
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References
AbbVie. Ubrelvy Product Information.

https://www.ubrelvy.com/

GlaxoSmithKline. Imitrex Product Information.

www.imitrex.com

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