Unasyn vs. Amoxil (Amoxicillin)

Are Unasyn and Amoxil the Same Thing?

Unasyn (ampicillin sodium/sulbactam sodium) and Amoxil (amoxicillin) are antibiotics used to treat bacterial infections.

Unasyn and Amoxil both contain penicillin-type antibiotics. Unasyn also contains a beta-lactamase inhibitor.

Side effects of Unasyn and Amoxil that are similar include nausea, vomiting, diarrhea, stomach pain, vaginal itching or discharge, headache, rash, and swollen/black/"hairy" tongue.

Side effects of Unasyn that are different from Amoxil include fever, sore throat, body aches, bloating, gas, itching, thrush (white patches inside your mouth or throat), and pain, swelling, or irritation where the needle is placed.

Both Unasyn and Amoxil may interact with probenecid.

Unasyn may also interact with allopurinol.

Amoxil may also interact with blood thinners, other antibiotics, or sulfa drugs.

What Are Possible Side Effects of Unasyn?

Common side effects of Unasyn include:

  • fever,
  • sore throat,
  • headache,
  • rash,
  • diarrhea,
  • body aches,
  • nausea,
  • vomiting,
  • stomach pain,
  • bloating,
  • gas,
  • vaginal itching or discharge,
  • itching,
  • swollen/black/"hairy" tongue,
  • thrush (white patches inside your mouth or throat), or
  • pain, swelling, or irritation where the needle is placed.

What Are Possible Side Effects of Amoxil?

Common side effects of Amoxil include:

  • mild headache (not a migraine),
  • pain or chest tightness,
  • pressure or heavy feeling in any part of your body,
  • weakness,
  • feeling hot or cold,
  • dizziness,
  • spinning sensation,
  • drowsiness,
  • nausea,
  • vomiting,
  • drooling,
  • unusual taste in your mouth after using nasal spray,
  • burning/numbness/pain/irritation in your nose or throat after using nasal spray, or
  • flushing (warmth, redness, or tingling under the skin).

What is Unasyn?

Unasyn (ampicillin sodium/sulbactam sodium) is a combination antibiotic indicated for the treatment of infections due to susceptible strains of microorganisms.

What is Amoxil?

Amoxil (amoxicillin) is a penicillin-type antibiotic used to treat infections caused by bacteria that are B-lactamase negative (B-lactamase positive bacteria are usually resistant to Amoxil (amoxicillin)); these infections usually occur in the skin, lungs, urinary tract and eye, ears, nose, and throat. Amoxil (amoxicillin) is available as a generic drug termed amoxicillin. Amoxil (amoxicillin) may be combined with other drugs (for example, clavulanic acid [Augmentin]), to make the antibiotic more effective.

QUESTION

Bowel regularity means a bowel movement every day. See Answer

What Drugs Interact With Unasyn?

Unasyn may interact with allopurinol, probenecid, or other antibiotics.

What Drugs Interact With Amoxil?

Amoxil (amoxicillin) may interact with probenecid, blood thinners, other antibiotics, or sulfa drugs. Tell your doctor all medications and supplements you use. Treatment in pregnant women and women who are breastfeeding should be done with caution.

How Should Unasyn Be Taken?

Unasyn is administered orally in the form of tablets.

How Should Amoxil Be Taken?

Amoxil (amoxicillin) is available in many preparations (capsules, tablets, chewable tablets, powder for oral suspension and pediatric oral suspension).

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References


Pfizer. Unasyn Product Information.

https://www.pfizer.com/products/product-detail/unasyn

DailyMed. Amoxil (amoxicillin) Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=375cdfd0-7996-5a42-e054-00144ff88e88

Health Solutions From Our Sponsors