Unasyn vs. Ancef (Cefazolin)

Are Unasyn and Ancef the Same Thing?

Unasyn (ampicillin sodium/sulbactam sodium) and Ancef (cefazolin) are antibiotics used to treat bacterial infections.

Unasyn and Ancef are different types of antibiotics. Unasyn is a combination of a penicillin-type antibiotic and a beta-lactamase inhibitor and Ancef is a cephalosporin antibiotic.

Side effects of Unasyn and Ancef that are similar include headache, skin rash, diarrhea, nausea, vomiting, stomach pain, gas, vaginal itching or discharge, itching, thrush (white patches inside your mouth or throat), and injection site reactions (pain, swelling, skin rash, irritation, or a hard lump).

Side effects of Unasyn that are different from Ancef include fever, sore throat, body aches, bloating, and swollen/black/"hairy" tongue.

Side effects of Ancef that are different from Unasyn include stomach cramps, loss of appetite, hives, heartburn, rectal itching, fainting, lightheadedness, confusion, weakness, tiredness, low blood pressure (hypotension), drowsiness, and allergic reactions.

Both Unasyn and Ancef may interact with probenecid.

Unasyn may also interact with allopurinol.

What Are Possible Side Effects of Unasyn?

Common side effects of Unasyn include:

  • fever,
  • sore throat,
  • headache,
  • rash,
  • diarrhea,
  • body aches,
  • nausea,
  • vomiting,
  • stomach pain,
  • bloating,
  • gas,
  • vaginal itching or discharge,
  • itching,
  • swollen/black/"hairy" tongue,
  • thrush (white patches inside your mouth or throat), or
  • pain, swelling, or irritation where the needle is placed.

What Are Possible Side Effects of Ancef?

Common side effects of Ancef include:

  • injection site reactions (pain, swelling, skin rash, or a hard lump),
  • diarrhea,
  • stomach pain,
  • stomach cramps,
  • nausea,
  • vomiting,
  • loss of appetite,
  • skin rash or itching,
  • hives,
  • white patches or sores inside the mouth or on the lips,
  • vaginal itching or discharge,
  • heartburn,
  • gas,
  • rectal itching,
  • fainting,
  • lightheadedness,
  • confusion,
  • weakness,
  • tiredness,
  • hypotension,
  • drowsiness,
  • headache, and
  • allergic reactions.

What is Unasyn?

Unasyn (ampicillin sodium/sulbactam sodium) is a combination antibiotic indicated for the treatment of infections due to susceptible strains of microorganisms.

What is Ancef?

Cefazolin and dextrose for injection is an antibiotic used to treat many different kinds of bacterial infections.

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow

What Drugs Interact With Unasyn?

Unasyn may interact with allopurinol, probenecid, or other antibiotics.

What Drugs Interact With Ancef?

Ancef (cefazolin) may interact with probenecid.

How Should Unasyn Be Taken?

Unasyn is administered orally in the form of tablets.

How Should Ancef Be Taken?

The dose of Ancef (cefazolin) varies depending on the condition being treated and its severity. For mild infections, the recommended adult dose is 250 mg to 500 mg every 8 hours. For more severe infections the dose is 500 mg to 1 g every 6 to 8 hours.

QUESTION

Bowel regularity means a bowel movement every day. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References


Pfizer. Unasyn Product Information.

https://www.pfizer.com/products/product-detail/unasyn

Medscape. Rocephin Product Information.

https://reference.medscape.com/drug/rocephin-ceftriaxone-342510

Health Solutions From Our Sponsors