Unasyn vs. Cleocin

Are Unasyn and Cleocin the Same Thing?

Unasyn (ampicillin sodium/sulbactam sodium) and Cleocin (clindamycin) are antibiotics used to treat bacterial infections.

Unasyn and Cleocin are different types of antibiotics. Unasyn is a combination of a penicillin-type antibiotic and a beta-lactamase inhibitor and Cleocin is a lincosamide antibiotic.

Side effects of Unasyn and Cleocin that are similar include sore throat, skin rash or itching, diarrhea, nausea, vomiting, stomach pain, and vaginal itching or discharge.

Side effects of Unasyn that are different from Cleocin include fever, headache, body aches, bloating, gas, swollen/black/"hairy" tongue, thrush (white patches inside your mouth or throat), or pain, swelling, or irritation where the needle is placed.

Side effects of Cleocin that are different from Unasyn include joint pain, heartburn, or changes in bowel habits (especially in older adults).

Unasyn may interact with allopurinol or probenecid.

Cleocin may interact with other neuromuscular blocking agents and erythromycin.

What Are Possible Side Effects of Unasyn?

Common side effects of Unasyn include:

  • fever,
  • sore throat,
  • headache,
  • rash,
  • diarrhea,
  • body aches,
  • nausea,
  • vomiting,
  • stomach pain,
  • bloating,
  • gas,
  • vaginal itching or discharge,
  • itching,
  • swollen/black/"hairy" tongue,
  • thrush (white patches inside your mouth or throat), or
  • pain, swelling, or irritation where the needle is placed.

What Are Possible Side Effects of Cleocin?

Common side effects of Cleocin include:

Other side effects of Cleocin include:

  • burning,
  • itching,
  • dryness,
  • redness,
  • oily skin,
  • skin peeling, or
  • other irritation of treated skin.

Tell your doctor if you have serious side effects of Cleocin including:

  • severe redness, itching, or dryness of treat skin areas; or
  • diarrhea that is watery or bloody.

What Is Unasyn?

Unasyn (ampicillin sodium/sulbactam sodium) is a combination antibiotic indicated for the treatment of infections due to susceptible strains of microorganisms.

What Is Cleocin?

Cleocin (clindamycin) is an antibiotic used to treat severe acne. Cleocin T is available in generic form.

QUESTION

Bowel regularity means a bowel movement every day. See Answer

What Drugs Interact With Unasyn?

Unasyn may interact with allopurinol, probenecid, or other antibiotics.

What Drugs Interact With Cleocin?

Cleocin may interact with other neuromuscular blocking agents or erythromycin.

How Should Unasyn Be Taken?

Unasyn is administered orally in the form of tablets.

How Should Cleocin Be Taken?

Apply a thin film of Cleocin twice daily to affected area. Cleocin T may interact with erythromycin topical or erythromycin taken by mouth. Tell your doctor all medications you are taking. The dose of Cleocin HCl for adults is 150 to 300 mg every 6 hours. For more severe infections is 300 to 450 mg every 6 hours. The dose of for pediatric patients is 8 to 16 mg/kg/day divided in three or four equal doses. For more severe infections, 16 to 20 mg/kg/day divided in three or four equal doses.

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References


Pfizer. Unasyn Product Information.

https://www.pfizer.com/products/product-detail/unasyn

Pfizer. Cleocin T Product Information.

https://www.pfizermedicalinformation.com/en-us/cleocin-t/dosage-admin

Health Solutions From Our Sponsors