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Upneeq

Last reviewed on RxList: 9/1/2020
Upneeq Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Upneeq?

Upneeq (oxymetazoline hydrochloride ophthalmic solution) is an alpha-adrenergic agonist used to treat acquired drooping upper eyelid (blepharoptosis) in adults.

What Are Side Effects of Upneeq?

Side effects of Upneeq include:

  • punctate keratitis,
  • eye redness,
  • dry eye,
  • blurred vision,
  • instillation site pain,
  • eye irritation, and
  • headache

Dosage for Upneeq

Thedose of Upneeq is one drop instilled into one or both ptotic eye(s) once daily. Discard the single patient-use container immediately after dosing.

Upneeq In Children

Safety and effectiveness of Upneeq have not been established in pediatric patients under 13 years of age.

What Drugs, Substances, or Supplements Interact with Upneeq?

Upneeq may interact with other medicines such as:

  • beta-blockers,
  • anti-hypertensives,
  • cardiac glycosides, and
  • monoamine oxidase inhibitors (MAOIs)

Tell your doctor all medications and supplements you use.

Upneeq During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Upneeq; it is unknown how it would affect a fetus. It is unknown if Upneeq passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Upneeq (oxymetazoline hydrochloride ophthalmic solution), 0.1%, for Topical Ophthalmic Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow
Upneeq Professional Information

SIDE EFFECTS

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

A total of 360 subjects with acquired blepharoptosis were treated with UPNEEQ once daily in each eye for at least 6 weeks in three controlled Phase 3 clinical trials, including 203 subjects treated with UPNEEQ for 6 weeks and 157 subjects treated with UPNEEQ for 12 weeks. Adverse reactions that occurred in 1-5% of subjects treated with UPNEEQ were punctate keratitis, conjunctival hyperemia, dry eye, blurred vision, instillation site pain, eye irritation and headache.

Read the entire FDA prescribing information for Upneeq (Oxymetazoline Hydrochloride Ophthalmic Solution)

QUESTION

What causes dry eyes? See Answer
Related Resources for Upneeq

© Upneeq Patient Information is supplied by Cerner Multum, Inc. and Upneeq Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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