Urobiotic Side Effects Center

Last updated on RxList: 8/15/2022
Urobiotic Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Urobiotic?

Urobiotic-250 (oxytetracycline, sulfamethizole and phenazopyridine) is a combination antibiotic, sulfonamide, and analgesic used to treat genitourinary infections caused by susceptible organisms. These infections include the following: pyelonephritis, pyelitis, ureteritis, cystitis, prostatitis, and urethritis.

What Are Side Effects of Urobiotic?

Common side effects of Urobiotic-250 include:

Urobiotic may cause serious side effects including:

Get medical help right away, if you have any of the symptoms listed above.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Urobiotic

A dose of 1 capsule of Urobiotic-250 four times daily is suggested.

What Drugs, Substances, or Supplements Interact with Urobiotic?

Urobiotic-250 may interact with other drugs. Tell your doctor all medications and supplements you use.

Urobiotic During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before starting treatment with Urobiotic-250. Consult your doctor before breastfeeding.

Additional Information

Our Urobiotic-250 (oxytetracycline, sulfamethizole and phenazopyridine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


About how much does an adult human brain weigh? See Answer
Urobiotic Professional Information


Glossitis, stomatitis, proctitis, nausea, diarrhea, vaginitis, and dermatitis, as well as reactions of an allergic nature, may occur during oxytetracycline HCl therapy, but are rare. If adverse reactions, individual idiosyncrasy, or allergy occur, discontinue medication. Rare instances of esophagitis and esophageal ulcerations have been reported in patients receiving capsule forms of drugs in the tetracycline class. Most of these patients took medications immediately before going to bed. (See DOSAGE AND ADMINISTRATION.)

With oxytetracycline therapy bulging fontanels in infants and benign intracranial hypertension in adults have been reported in individuals receiving full therapeutic dosages. These conditions disappeared rapidly when the drug was discontinued.

As in all sulfonamide therapy, the following reactions may occur: nausea, vomiting, diarrhea, hepatitis, pancreatitis, blood dyscrasias, neuropathy, drug fever, skin rash, injection of the conjunctiva and sclera, petechiae, purpura, hematuria and crystalluria. The dosage should be decreased or the drug withdrawn, depending upon the severity of the reaction.

Read the entire FDA prescribing information for Urobiotic (Oxytetracycline, Sulfamethizole and Phenazopyridine)


Digestive Disorders: Common Misconceptions See Slideshow

© Urobiotic Patient Information is supplied by Cerner Multum, Inc. and Urobiotic Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors