Are Vemlidy and Baraclude the Same Thing?
Vemlidy (tenofovir alafenamide) and Baraclude (entecavir) are antiviral medications used to treat chronic hepatitis B virus (HBV).
Vemlidy is used to treat chronic hepatitis B virus infection in adults with compensated liver disease.
Baraclude is used to treat chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Side effects of Vemlidy and Baraclude that are similar include headache, fatigue, and nausea.
Side effects of Vemlidy that are different from Baraclude include abdominal pain, cough, and back pain.
Side effects of Baraclude that are different from Vemlidy include vomiting, diarrhea, upset stomach, temporary hair loss, skin rash, dizziness, and sleep problems (insomnia).
Both Vemlidy and Baraclude may interact with antiviral medications.
Vemlidy may also interact with drugs that induce P-gp activity, aminoglycosides, high-dose or multiple nonsteroidal anti-inflammatories (NSAIDs), anticonvulsants, antimycobacterials, and St. John's wort.
Baraclude may also interact with drugs that weaken your immune system (such as cancer medicine or steroids), amphotericin B, cyclosporine, pentamidine, sirolimus, tacrolimus, and antibiotics.
What Are Possible Side Effects of Vemlidy?
Common side effects of Vemlidy include:
What Are Possible Side Effects of Baraclude?
Common side effects of Baraclude include:
- upset stomach,
- temporary hair loss,
- skin rash,
- dizziness, or
- sleep problems (insomnia).
Baraclude may also cause severe liver symptoms. Tell your doctor if you have any liver symptoms including:
- low fever,
- stomach pain,
- loss of appetite,
- dark urine,
- clay-colored stools, or
- jaundice (yellowing of the skin or eyes).
What Is Vemlidy?
Vemlidy (tenofovir alafenamide) is a hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitor and is indicated for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
What Is Baraclude?
Baraclude (entecavir) is an antiviral nucleoside drug indicated for the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease. Baraclude is available in generic form.
What Drugs Interact With Vemlidy?
Vemlidy may interact with drugs that induce P-gp activity, antivirals, aminoglycosides, high-dose or multiple nonsteroidal anti-inflammatories (NSAIDs), anticonvulsants, antimycobacterials, and St. John's wort. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Vemlidy. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to during pregnancy. It is unknown if Vemlidy passes into breast milk. Consult your doctor before breastfeeding.
What Drugs Interact With Baraclude?
Baraclude may interact with drugs that weaken your immune system (such as cancer medicine or steroids), amphotericin B, cyclosporine, pentamidine, sirolimus, tacrolimus, antibiotics, or other antiviral medicines. Tell your doctor all medications and supplements you use. There are no adequate and well-controlled studies of Baraclude in pregnant women. Baraclude should be used during pregnancy or breastfeeding only if clearly needed and after careful consideration of the risks and benefits.
How Should Vemlidy Be Taken?
The recommended dosage of Vemlidy is 25 mg (one tablet) taken orally once daily with food.
How Should Baraclude Be Taken?
Baraclude tablets are available for oral administration in strengths of 0.5 mg and 1 mg. Baraclude should be administered on an empty stomach (at least 2 hours after a meal and 2 hours before the next meal).
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Bristol-Myers Squibb Company. Baraclude Product Information