Sinecatechins (Topical)

Reviewed on 9/20/2022

What Is Sinecatechins (Topical)and How Does It Work?

Sinecatechins (Topical) is a prescription medication used to treat genital and anal warts in adults. This medication is used only on warts outside the genitals and around the outside of the anus.

  • Sinecatechins (Topical) are available under various brand names: Veregen 

What Are Side Effects Associated with Using Sinecatechins (Topical)?

Common side effects of Sinecatechins (Topical) include:

  • mild redness or burning of treated skin; or
  • mild pain, itching, or discomfort.

Serious side effects of Sinecatechins (Topical) include:

  • hives. 
  • difficulty breathing. 
  • swelling of the face, lips, tongue, or throat.
  • severe redness or swelling of treated skin.
  • severe burning, itching, or pain; or
  • painful sores or blisters where the ointment was applied.

Rare side effects of Sinecatechins (Topical) include:

  • none

Seek medical care or call 911 at once if you have the following serious side effects:

  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheartedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

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What Are Dosages of Sinecatechins (Topical)?

Adult dosage

Topical ointment

  • 15%

External genital and perianal warts (Condylomata acuminata):

Adult dosage

  • Topical: Sinecatechins is usually applied 3 times per day. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

What Other Drugs Interact with Sinecatechins (Topical)?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

  • Sinecatechins (Topical) have no noted severe interactions with any other drugs.
  • Sinecatechins (Topical) have no noted  serious interactions with any other drugs.
  • Sinecatechins (Topical) have no noted moderate interactions with any other drugs.
  • Sinecatechins (Topical) have no noted  minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

What Are Warnings and Precautions for Sinecatechins (Topical)?

Contraindications

Effects of drug abuse

  • None

Short-Term Effects

  • See “What Are Side Effects Associated with Using Sinecatechins (Topical)?”

Long-Term Effects

  • See “What Are Side Effects Associated with Using Sinecatechins (Topical)?”

Cautions

  • Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Avoid getting this medicine in your eyes, nose, mouth, rectum, vagina, or urethra.
  • Avoid touching or allowing another person to touch the treated skin areas after you have applied the ointment.
  • Avoid exposing treated skin to sunlight or artificial UV rays (sunlamps or tanning beds).
  • Avoid using other medicine or skin products on the areas you treat with sinecatechins.
  • Avoid sexual intercourse while you have sinecatechins on your skin. Wash off the ointment before intercourse, even if you are using a condom. Sinecatechins can weaken the latex in a rubber condom and it could break.
  • Using this medicine will not prevent you from passing genital or anal warts to another person during skin-to-skin contact or sexual intercourse. Talk with your doctor about safe ways to prevent transmission of genital warts during sex.

Pregnancy and Lactation

  • It is not known whether sinecatechins will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
  • Lactation
    • It is not known whether sinecatechins pass into breast milk or if they could harm a nursing baby. Tell your doctor if you are breastfeeding a baby.

QUESTION

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References
Medical Editor: John P. Cunha, DO, FACOEP

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