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Vicodin

Last reviewed on RxList: 8/3/2017
Vicodin Side Effects Center
RxList

Pharmacy Editor: Omudhome Ogbru, PharmD

Last reviewed on RxList 8/3/2017

Vicodin (hydrocodone/acetaminophen) is a combination of the narcotic hydrocodone and non-narcotic pain reliever acetaminophen used for the relief of moderate to moderately severe pain. Vicodin is available in generic form. Common side effects of Vicodin include:

  • lightheadedness,
  • dizziness,
  • anxiety,
  • nausea,
  • vomiting,
  • upset stomach,
  • drowsiness,
  • constipation,
  • headache,
  • mood changes,
  • blurred vision,
  • ringing in your ears,
  • dry mouth, and
  • difficulty urinating.

Tell your doctor if you have serious side effects of Vicodin including shallow breathing, slow heartbeat, fainting, confusion, fear, unusual thoughts or behavior, seizures (convulsions), upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or yellowing of the skin or eyes (jaundice).

Our Vicodin Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Vicodin Consumer Information
RxList

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • shallow breathing, slow heartbeat;
  • feeling light-headed, fainting;
  • confusion, fear, unusual thoughts or behavior;
  • seizure (convulsions);
  • problems with urination; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • anxiety, dizziness, drowsiness;
  • mild nausea, vomiting, upset stomach, constipation;
  • headache, mood changes;
  • blurred vision;
  • ringing in your ears; or
  • dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Vicodin (Hydrocodone Bitartrate and Acetaminophen)

Vicodin Professional Information
RxList

SIDE EFFECTS

The following adverse reactions have been identified during post approval use of hydrocodone and acetaminophen tablets. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

The most frequently reported adverse reactions are light-headedness, dizziness, sedation, nausea and vomiting.

Other adverse reactions include:

Central Nervous System: Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychological dependence, mood changes.

Gastrointestinal System: Constipation.

Genitourinary System: Ureteral spasm, spasm of vesical sphincters, and urinary retention.

Special Senses : Cases of hearing impairment or permanent loss have been reported predominately in patients with chronic overdose.

Dermatological: Skin rash, pruritus, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic reactions.

Hematological: Thrombocytopenia, agranulocytosis.

  • Serotonin syndrome: Cases of serotonin syndrome, a potentially life-threatening condition, have been reported during concomitant use of opioids with serotonergic drugs.
  • Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use.
  • Anaphylaxis: Anaphylaxis has been reported with ingredients contained in hydrocodone bitartrate and acetaminophen tablets.
  • Androgen deficiency: Cases of androgen deficiency have occurred with chronic use of opioids [see CLINICAL PHARMACOLOGY].

Read the entire FDA prescribing information for Vicodin (Hydrocodone Bitartrate and Acetaminophen)

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