Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Vicodin

Last reviewed on RxList: 8/3/2017
Vicodin Side Effects Center

Pharmacy Editor: Omudhome Ogbru, PharmD

Last reviewed on RxList 8/3/2017

Vicodin (hydrocodone/acetaminophen) is a combination of the narcotic hydrocodone and non-narcotic pain reliever acetaminophen used for the relief of moderate to moderately severe pain. Vicodin is available in generic form. Common side effects of Vicodin include:

Tell your doctor if you have serious side effects of Vicodin including shallow breathing, slow heartbeat, fainting, confusion, fear, unusual thoughts or behavior, seizures (convulsions), upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or yellowing of the skin or eyes (jaundice).

Our Vicodin Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Vicodin Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing;
  • slow heartbeat or weak pulse;
  • a light-headed feeling, like you might pass out;
  • sudden weakness or ill feeling, fever, chills, sore throat, unusual bruising or bleeding;
  • confusion, unusual thoughts or behavior;
  • painful or difficult urination;
  • liver problems--nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Common side effects include:

  • dizziness, drowsiness;
  • nausea; or
  • constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Vicodin (Hydrocodone Bitartrate and Acetaminophen)

Vicodin Professional Information

SIDE EFFECTS

The following adverse reactions have been identified during post approval use of hydrocodone and acetaminophen tablets. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

The most frequently reported adverse reactions are light-headedness, dizziness, sedation, nausea and vomiting.

Other adverse reactions include:

Central Nervous System: Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychological dependence, mood changes.

Gastrointestinal System: Constipation.

Genitourinary System: Ureteral spasm, spasm of vesical sphincters, and urinary retention.

Special Senses : Cases of hearing impairment or permanent loss have been reported predominately in patients with chronic overdose.

Dermatological: Skin rash, pruritus, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic reactions.

Hematological: Thrombocytopenia, agranulocytosis.

  • Serotonin syndrome: Cases of serotonin syndrome, a potentially life-threatening condition, have been reported during concomitant use of opioids with serotonergic drugs.
  • Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use.
  • Anaphylaxis: Anaphylaxis has been reported with ingredients contained in hydrocodone bitartrate and acetaminophen tablets.
  • Androgen deficiency: Cases of androgen deficiency have occurred with chronic use of opioids [see CLINICAL PHARMACOLOGY].

Read the entire FDA prescribing information for Vicodin (Hydrocodone Bitartrate and Acetaminophen)

Health Solutions From Our Sponsors

CONTINUE SCROLLING FOR RELATED ARTICLE