Medical Editor: John P. Cunha, DO, FACOEP
Vitamin K1 (phytonadione) Injectable Emulsion is a vitamin used to treat conditions resulting from vitamin K deficiency or that interfere with vitamin K activity. Vitamin K1 is available in generic form. Common side effects of Vitamin K1 include dizziness, sweating, and injection site reactions (pain, swelling, and tenderness), temporary flushing, taste changes, rapid heartbeat, shortness of breath, or bluish lips/skin/nails.
Talk to your doctor about your individual dosage recommendation. Prothrombin-depressing anticoagulants may interact with Vitamin K1. Before taking Vitamin K1 tell your doctor if you have impaired kidney function. If you are pregnant only take Vitamin K1 if clearly needed. Exercise caution if taking Vitamin K1 while breastfeeding.
Our Vitamin K1 (phytonadione) Injectable Emulsion Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for vitamin k1 injection (Aqueous Colloidal Solution of Vitamin K1)
Transient "flushing sensations" and "peculiar" sensations of taste have been observed, as well as rare instances of dizziness, rapid and weak pulse, profuse sweating, brief hypotension, dyspnea, and cyanosis.
Pain, swelling, and tenderness at the injection site may occur.
The possibility of allergic sensitivity including an anaphylactoid reaction, should be kept in mind.
Infrequently, usually after repeated injection, erythematous, indurated, pruritic plaques have occurred; rarely, these have progressed to scleroderma-like lesions that have persisted for long periods. In other cases, these lesions have resembled erythema perstans.
Hyperbilirubinemia has been observed in the newborn following administration of phytonadione. This has occurred rarely and primarily with doses above those recommended. (See PRECAUTIONS, Pediatric Use.)
Read the entire FDA prescribing information for vitamin k1 injection (Aqueous Colloidal Solution of Vitamin K1)