Vumerity vs. Aubagio

Reviewed on 12/2/2019

Are Vumerity and Aubagio the Same Thing?

Vumerity (diroximel fumarate) and Aubagio (teriflunomide) are used to treat relapsing forms of multiple sclerosis (MS).

Vumerity and Aubagio belong to different drug classes. Vumerity is an immunomodulator and Aubagio is a pyrimidine synthesis inhibitor.

Side effects of Vumerity and Aubagio that are similar include diarrhea and nausea.

Side effects of Vumerity that are different from Aubagio include flushing, abdominal pain, vomiting, itching, rash, albumin in the urine, redness, and indigestion/heartburn.

Side effects of Aubagio that are different from Vumerity include liver problems, influenza, hair loss or thinning hair, burning or prickly feeling in your skin, and numbness or tingling in your hands or feet that is different from your MS symptoms.

Vumerity may interact with dimethyl fumarate.

Aubagio may interact with "live" vaccines, cholestyramine, methotrexate, rifampin, warfarin, birth control pills or hormone replacement therapy, cancer medicines, medicine to treat autoimmune disorders (such as rheumatoid arthritis, lupus, or psoriasis), medicines to prevent organ transplant rejection, cholesterol-lowering medications, and steroids.

What Are Possible Side Effects of Vumerity?

Common side effects of Vumerity include:

  • flushing,
  • abdominal pain,
  • diarrhea,
  • nausea,
  • vomiting,
  • itching,
  • rash,
  • albumin in the urine,
  • redness, and
  • indigestion/heartburn

What Are Possible Side Effects of Aubagio?

Common side effects of Aubagio include:

  • liver problems,
  • influenza,
  • hair loss or thinning hair,
  • nausea,
  • diarrhea,
  • burning or prickly feeling in your skin, or
  • numbness or tingling in your hands or feet that is different from your MS symptoms.

Tell your doctor if you have serious side effects of Aubagio including:

  • fever,
  • chills,
  • body aches,
  • flu symptoms,
  • sores in your mouth and throat,
  • itching,
  • tired feeling,
  • loss of appetite,
  • dark urine,
  • clay-colored stools,
  • yellowing of the skin or eyes,
  • fast or racing heartbeats,
  • confusion,
  • little or no urinating,
  • chest pain,
  • dry cough,
  • wheezing,
  • feeling short of breath,
  • skin redness or peeling,
  • swelling,
  • rapid weight gain, or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

What Is Vumerity?

Vumerity (diroximel fumarate) is an immunomodulator indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

What Is Aubagio?

Aubagio (teriflunomide) is a pyrimidine synthesis inhibitor used to treat relapsing forms of multiple sclerosis (MS).

QUESTION

What kind of disease is multiple sclerosis? See Answer

What Drugs Interact With Vumerity?

Vumerity may interact with other medicines such as:

  • dimethyl fumarate

Tell your doctor all medications and supplements you use.

What Drugs Interact With Aubagio?

Aubagio may increase exposure of ethinyl estradiol and levonorgestrel. Patients taking Coumadin (warfarin) should be closely monitored as interactions may occur. Aubagio may cause major birth defects if used during pregnancy. Pregnancy must be excluded before starting treatment with Aubagio. Pregnancy must be avoided while taking Aubagio treat relapsing forms of multiple sclerosis (MS). If Aubagio is used during pregnancy, or if the patient becomes pregnant while taking Aubagio, the drug should be discontinued immediately and an accelerated elimination procedure should be initiated. Consult your doctor before breastfeeding.

How Should Vumerity Be Taken?

The starting dose of Vumerity is 231 mg twice a day, orally, for 7 days. The maintenance dose of Vumerity after 7 days is 462 mg (administered as two 231 mg capsules) twice a day, orally.

How Should Aubagio Be Taken?

The recommended dose for Aubagio is 7 mg or 14 mg taken orally, once daily, with or without food.

SLIDESHOW

What Is Multiple Sclerosis? MS Symptoms, Causes, Diagnosis See Slideshow
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References
Biogen. Vumerity Product Information.

www.vumerity.com/?

Genzyme. Aubagio Product Information

https://www.aubagio.com

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