Vyepti vs. Ajovy

Reviewed on 8/20/2020

Are Vyepti and Ajovy the Same Thing?

Vyepti (eptinezumab-jjmr) and Ajovy (erenumab-aooe) are calcitonin gene-related peptide antagonists used to prevent migraine in adults.

Side effects of Vyepti that are different from Ajovy include runny or stuffy nose and hypersensitivity reactions (itching, flushing).

Side effects of Ajovy Ajovy that are different from Vyepti include injection site reactions (pain or redness), constipation, and muscle spasms or cramps.

Both Vyepti and may interact with other drugs.

What Are Possible Side Effects of Vyepti?

Side effects of Vyepti include:

  • runny or stuffy nose and
  • hypersensitivity reactions (itching, flushing)

What Are Possible Side Effects of Ajovy?

Common side effects of Ajovy include:

  • injection site reactions (pain, swelling, and redness)


16 Surprising Headache Triggers and Tips for Pain Relief See Slideshow

What Is Vyepti?

Vyepti (eptinezumab-jjmr) is a calcitonin gene-related peptide antagonist indicated for the preventive treatment of migraine in adults.

What Is Ajovy?

Ajovy (fremanezumab-vfrm) is a calcitonin gene-related peptide antagonist indicated for the preventive treatment of migraine in adults.

What Drugs Interact With Vyepti?

Vyepti may interact with other medicines.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Ajovy?

Ajovy may interact with other drugs. Tell your doctor all medications and supplements you use.

How Should Vyepti be Taken?

The recommended dosage of Vyepti is 100 mg as an intravenous infusion over approximately 30 minutes every 3 months. Some patients may benefit from a dosage of 300 mg.

How Should Ajovy be Taken?

Two subcutaneous dosing options of Ajovy are available to administer the recommended dosage: 225 mg monthly, or 675 mg every 3 months (quarterly). The 675 mg quarterly dosage is administered as three consecutive injections of 225 mg each.


All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

Lundbeck Seattle BioPharmaceuticals, Inc. Vyepti Product Information.


Teva. Ajovy Product Informtion


Health Solutions From Our Sponsors