Vyepti vs. Zomig

Reviewed on 8/27/2020

Are Vyepti and Zomig the Same Thing?

Vyepti (eptinezumab-jjmr) and Zomig (zolmitriptan) are used to treat and prevent migraine in adults.

Vyepti and Zomig belong to different drug classes. Vyepti is a calcitonin gene-related peptide antagonist and Zomig is a selective serotonin receptor agonist (a "triptan").

Side effects of Vyepti that are different from Zomig include runny or stuffy nose and hypersensitivity reactions (itching, flushing).

Side effects of Zomig that are different from Vyepti include unusual or unpleasant taste in your mouth, discomfort in the nose or throat after using the nasal spray, warmth/redness/tingling/numbness under the skin, nausea, dry mouth, weakness, drowsiness, dizziness, and pressure or heavy feeling in any part of your body.

Vyepti may interact with other drugs.

Zomig may interact with other migraine headache medicines, cimetidine, and antidepressants.

What Are Possible Side Effects of Vyepti?

Common side effects of Vyepti include:

Side effects of Vyepti include:

  • runny or stuffy nose and
  • hypersensitivity reactions (itching, flushing)

What Are Possible Side Effects of Zomig?

Common side effects of Zomig include:

  • unusual or unpleasant taste in your mouth,
  • discomfort in the nose or throat after using the nasal spray,
  • warmth/redness/tingling/numbness under the skin,
  • nausea,
  • dry mouth,
  • weakness,
  • drowsiness,
  • dizziness, or
  • pressure or heavy feeling in any part of your body

SLIDESHOW

16 Surprising Headache Triggers and Tips for Pain Relief See Slideshow

What Is Vyepti?

Vyepti (eptinezumab-jjmr) is a calcitonin gene-related peptide antagonist indicated for the preventive treatment of migraine in adults.

What Is Zomig?

Zomig (zolmitriptan) Nasal Spray is a headache medicine that narrows blood vessels around the brain used to treat migraine headaches. Zomig Nasal Spray will only treat a headache that has already begun. Zomig Nasal Spray will not prevent headaches or reduce the number of attacks.

What Drugs Interact With Vyepti?

Vyepti may interact with other medicines.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Zomig?

Zomig may interact with other migraine headache medicines, cimetidine, or antidepressants. Tell your doctor all medications you are taking. During pregnancy, Zomig should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

How Should Vyepti be Taken?

The recommended dosage of Vyepti is 100 mg as an intravenous infusion over approximately 30 minutes every 3 months. Some patients may benefit from a dosage of 300 mg.

How Should Zomig be Taken?

The initial dose of Zomig is 2.5 mg or less. The dose can be repeated after 2 hours if symptoms persist. The maximum dose is 10 mg per day.

QUESTION

Who suffers more frequently from migraine headaches? See Answer
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References
Lundbeck Seattle BioPharmaceuticals, Inc. Vyepti Product Information.

https://www.vyeptihcp.com/

Impax Laboratories, Inc. Zomig Product Information.

https://zomig.com

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