Cochlearia wasabi, Eutrema japonica, Eutremia wasabi, Gochunaengi, Japanese Horseradish, Japanischer Meerrettich, Wasabia japonica.
Wasabi is a crop that is native to Japan. It is now grown in other countries, including Taiwan and New Zealand. Wasabi is mainly grown for its roots. The roots are used to prepare sauces and condiments that have a strong and spicy flavor.
People take wasabi by mouth to prevent heart disease, cancer, and osteoporosis.
Wasabi is used in food as a strong spice.
How does it work?
Wasabi seems to have antibacterial, anti-cancer and anti-inflammatory effects. It also seems to slow blood clotting and stimulate bone growth.
Insufficient Evidence to Rate Effectiveness for...
- Heart disease prevention.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Bleeding disorders: Wasabi might slow blood clotting. In theory, wasabi might increase the risk of bleeding and bruising in people with bleeding disorders.
Surgery: Wasabi might slow blood clotting. In theory, wasabi might cause too much bleeding during surgery. Stop taking wasabi as a medicine at least 2 weeks before surgery.
Medications that slow blood clotting (Anticoagulant/Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Wasabi might slow blood clotting. In theory, taking wasabi along with medications that also slow clotting might increase the chances of bruising and bleeding.
The appropriate dose of wasabi depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for wasabi (in children/in adults). Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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Weil, M. J., Zhang, Y., and Nair, M. G. Colon cancer proliferating desulfosinigrin in wasabi (Wasabia japonica). Nutr Cancer 2004;48(2):207-213. View abstract.
Depree JA, Howard TM, Savage GP. Flavour and pharmaceutical properties of the volatile sulphur compounds of wasabi (Wasabia japonica). Food Res Int 1999;31(5):329-337.
Eid SR, Crown ED, Moore EL, Liang HA, Choong KC, Dima S, Henze DA, Kane SA,Urban MO. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain 2008;4:48. View abstract.
Hou, D. X., Fukuda, M., Fujii, M., and Fuke, Y. Transcriptional regulation of nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase in murine hepatoma cells by 6-(methylsufinyl)hexyl isothiocyanate, an active principle of wasabi (Eutrema wasabi Maxim). Cancer Lett 2000;161(2):195-200. View abstract.
Morimitsu, Y., Hayashi, K., Nakagawa, Y., Fujii, H., Horio, F., Uchida, K., and Osawa, T. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, Wasabi. Mech Ageing Dev 2000;116(2-3):125-134. View abstract.
Morimitsu, Y., Hayashi, K., Nakagawa, Y., Horio, F., Uchida, K., and Osawa, T. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, wasabi. Biofactors 2000;13(1-4):271-276. View abstract.
Nabekura, T., Kamiyama, S., and Kitagawa, S. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochem Biophys Res Commun 2005;327(3):866-870. View abstract.
Nomura, T., Shinoda, S., Yamori, T., Sawaki, S., Nagata, I., Ryoyama, K., and Fuke, Y. Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitro. Cancer Detect Prev 2005;29(2):155-160. View abstract.
Shin, I. S., Masuda, H., and Naohide, K. Bactericidal activity of wasabi (Wasabia japonica) against Helicobacter pylori. Int J Food Microbiol 2004;94(3):255-261. View abstract.
Watanabe, M., Ohata, M., Hayakawa, S., Isemura, M., Kumazawa, S., Nakayama, T., Furugori, M., and Kinae, N. Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi. Phytochemistry 2003;62(5):733-739. View abstract.
Weil, M. J., Zhang, Y., and Nair, M. G. Tumor cell proliferation and cyclooxygenase inhibitory constituents in horseradish (Armoracia rusticana) and Wasabi (Wasabia japonica). J Agric Food Chem 2005;53(5):1440-1444. View abstract.
Yamaguchi, M. Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis. Yakugaku Zasshi 2006;126(11):1117-1137. View abstract.