What Is the Best Treatment for Ulcerative Colitis?

Reviewed on 12/14/2020

Diet for UC
A low-fat diet with vitamin B6, sulfur, and milk is advised.

Treatment involves medical and surgical treatments, depending on the severity of the disease. Patients would also require lifestyle changes.

Medical treatment:

Most patients require a combination of more than one medication. Medical treatment typically involves medication to suppress and/or modulate the immune system. The medicines are mostly painkillers, antibiotics, antidiarrhea medication, and nutritional supplements.


Surgery can eliminate UC and involves removing the entire colon and rectum (proctocolectomy) followed by reconstruction.

Lifestyle and dietary modification:

Management of psychological stress and emotional support is important to prevent and reduce flare-ups. Regular exercises and a healthy diet are important as well. A low-fat diet with vitamin B6, sulfur, and milk is advised.

What causes ulcerative colitis?

The exact cause of ulcerative colitis (UC) is unknown; the possible causes are as follows:

What are the signs and symptoms of ulcerative colitis?

Patients may present with the following symptoms:

  1. Rectal bleeding
  2. Frequent stools
  3. Mucous discharge from the rectum
  4. Tenesmus (constant feeling of the evacuation of the bowels)
  5. Lower abdominal pain and cramps
  6. Dehydration
  7. Severe diarrhea and cramps
  8. Fever
  9. Abdominal distention/bloating
  10. Increased heart rate
  11. Severe abdominal pain
  12. Weight loss
  13. Pus discharge through the anus

Ulcerative colitis (UC) is associated with various extracolonic manifestations, such as inflammation of the eyes, joints, skin, and lungs.

Grading or Staging of UC: The severity of UC can be graded as follows:

  • Mild: Bleeding per rectum and fewer than four bowel motions a day.
  • Moderate: Bleeding per rectum with more than four bowel motions a day.
  • Severe: Bleeding per rectum more than four bowel motions per day and a systemic illness with protein loss.


Ulcerative colitis affects the colon. The colon is also referred to as the... See Answer

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Basson MD. Ulcerative Colitis Treatment & Management. Medscape. https://emedicine.medscape.com/article/183084-treatment#d8

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