Wixela Inhub vs. Cinqair

Are Wixela Inhub and Cinqair the Same Thing?

Wixela Inhub (fluticasone propionate and salmeterol inhalation powder) and Cinqair (reslizumab) injection are used to treat asthma.

Wixela Inhub is used for twice-daily treatment of asthma in patients aged 4 years and older and it is also used for maintenance treatment of airflow obstruction and reducing exacerbations in patients with chronic obstructive pulmonary disease (COPD).

Cinqair is used for add-on maintenance treatment of patients with severe asthma aged 18 years and older, and with an eosinophilic phenotype.

Wixela Inhub and Cinqair belong to different drug classes. Wixela Inhub contains a combination of a corticosteroid and a long-acting beta-adrenergic agonist (LABA) and Cinqair is an interleukin-5 antagonist monoclonal antibody (IgG4 kappa).

Side effects of Wixela Inhub and Cinqair that are similar include sore throat.

Side effects of Wixela Inhub that are different from Cinqair include upper respiratory tract infection or inflammation, hoarseness, oral thrush, bronchitis, cough, headaches, nausea, vomiting, pneumonia, and musculoskeletal pain.

Side effects of Cinqair that are different from Wixela Inhub include mouth pain.

Wixela Inhub may interact with other medicines containing a LABA, antivirals, azole antifungals, clarithromycin, telithromycin, nefazodone, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, beta-blockers, and diuretics.

Cinqair may interact with other drugs.

What Are Possible Side Effects of Wixela Inhub?

Common side effects of Wixela Inhub include:

  • upper respiratory tract infection or inflammation,
  • sore throat,
  • hoarseness,
  • oral thrush,
  • bronchitis,
  • cough,
  • headaches,
  • nausea and vomiting,
  • pneumonia,
  • viral respiratory infections, and
  • musculoskeletal pain

What Are Possible Side Effects of Cinqair?

Common side effects of Cinqair include:

  • mouth and throat pain.

What Is Wixela Inhub?

Wixela Inhub (fluticasone propionate and salmeterol inhalation powder) contains a combination of a corticosteroid and a long-acting beta-adrenergic agonist (LABA) indicated for twice-daily treatment of asthma in patients aged 4 years and older or maintenance treatment of airflow obstruction and reducing exacerbations in patients with chronic obstructive pulmonary disease (COPD). Wixela Inhub is available in generic form.

What Is Cinqair?

Cinqair (reslizumab) injection is an interleukin-5 antagonist monoclonal antibody (IgG4 kappa) indicated for add-on maintenance treatment of patients with severe asthma aged 18 years and older, and with an eosinophilic phenotype.

What Drugs Interact With Wixela Inhub?

Wixela Inhub may interact with additional medicines containing a LABA, ritonavir, ketoconazole, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, beta-blockers, and diuretics. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Wixela Inhub; it is unknown how it would affect a fetus. It is unknown if Wixela Inhub passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Cinqair?

Cinqair may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant before receiving Cinqair. It is unknown if Cinqair passes into breast milk or if it could affect a nursing infant. Consult your doctor before breastfeeding.

How Should Wixela Inhub Be Taken?

The dose of Wixela Inhub for treatment of asthma in patients aged 12 years and older is 1 inhalation of Wixela Inhub 100/50, Wixela Inhub 250/50, or Wixela Inhub 500/50 twice daily. The dose of Wixela Inhub for treatment of asthma in patients aged 4 to 11 years is 1 inhalation of Wixela Inhub 100/50 twice daily. The dose of Wixela Inhub for maintenance treatment of COPD is 1 inhalation of Wixela Inhub 250/50 twice daily.

How Should Cinqair Be Taken?

The recommended dosage regimen of Cinqair is 3 mg/kg once every 4 weeks by intravenous infusion over 20-50 minutes.

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References
Dailymed. Wixela Inhub Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3beef422-8a07-4a45-9ba6-414511e4b7e2

Teva. Cinqair Product Information.

https://www.cinqair.com/

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