Xcopri vs. Dilantin

Are Xcopri and Dilantin the Same Thing?

Xcopri (cenobamate tablets) and Dilantin (phenytoin) are antiepileptic drugs (AEDs) used to treat seizures.

Side effects of Xcopri and Dilantin that are similar include drowsiness, dizziness, and headache.

Side effects of Xcopri that are different from Dilantin include fatigue and double vision.

Side effects of Dilantin that are different from Xcopri include nausea, vomiting, constipation, spinning sensation, slurred speech, loss of balance or coordination, swollen or tender gums, sleep problems (insomnia), nervousness, tremors, and rash.

Both Xcopri and Dilantin may interact with other antiepileptic drugs (AEDs).

Xcopri may also interact with CYP2B6 and CYP3A substrates, CYP2C19 substrates, oral contraceptives, other drugs that shorten the QT interval, alcohol, and other CNS depressants.

Dilantin may also interact with stomach acid reducers, sedatives, antidepressants, estrogen hormone replacement, phenothiazines, disulfiram, methylphenidate, sulfa drugs, sucralfate, molindone, phenobarbital, steroids, antibiotics, digoxin, furosemide, and theophylline.

What Are Possible Side Effects of Xcopri?

Common side effects of Xcopri include:

    • drowsiness,
    • dizziness,
    • fatigue,
    • double vision, and
    • headache

    What Are Possible Side Effects of Dilantin?

    Common side effects of Dilantin include:

    • headache,
    • nausea,
    • vomiting,
    • constipation,
    • dizziness,
    • spinning sensation,
    • drowsiness,
    • slurred speech,
    • loss of balance or coordination,
    • swollen or tender gums,
    • sleep problems (insomnia),
    • nervousness,
    • tremors, or
    • rash.

    What Is Xcopri?

    Xcopri (cenobamate tablets) is an antiepileptic drug (AED) used to treat partial-onset seizures in adult patients.

    What Is Dilantin?

    Dilantin (phenytoin) is an anti-epileptic drug, also called an anticonvulsant, used to control seizures.

SLIDESHOW

What Is Epilepsy? Symptoms, Causes, and Treatments See Slideshow

What Drugs Interact With Xcopri?

Xcopri may interact with other medicines such as:

  • antiepileptic drugs (AEDs),
  • CYP2B6 and CYP3A substrates,
  • CYP2C19 substrates,
  • oral contraceptives,
  • other drugs that shorten the QT interval,
  • alcohol, and
  • other CNS depressants

Tell your doctor all medications and supplements you use and all vaccines you recently received.

What Drugs Interact With Dilantin?

Dilantin may interact with other medicines such as:

  • stomach acid reducers,
  • sedatives,
  • antidepressants,
  • estrogen hormone replacement,
  • phenothiazines,
  • disulfiram,
  • methylphenidate,
  • sulfa drugs,
  • carbamazepine,
  • sucralfate,
  • molindone,
  • phenobarbital,
  • valproic acid,
  • divalproex sodium,
  • steroids,
  • antibiotics,
  • digoxin,
  • furosemide, or
  • theophylline

Tell your doctor all medications and supplements you use.

How Should Xcopri Be Taken?

The recommended initial dosage of Xcopri is 12.5 mg once daily, adjusted to the recommended maintenance dosage of 200 mg once daily.

How Should Dilantin Be Taken?

Patients may be started on one 100-mg Dilantin Extended Oral Capsule three times daily. For most adults, the maintenance dosage is one capsule three to four times a day. The initial pediatric dose is 5 mg/kg/day in two or three equally divided doses, with dosage individualized to a maximum of 300 mg daily. Daily maintenance dosage is usually 4 to 8 mg/kg.

QUESTION

If you have had a seizure, it means you have epilepsy. See Answer
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References
SK Biopharmaceuticals Co., Ltd. Xcopri.

www.xcopri.com

Pfizer. Dilantin Prescribing Information.

https://www.dilantin.com/

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