Xcopri vs. Lyrica

Are Xcopri and Lyrica the Same Thing?

Xcopri (cenobamate tablets) and Lyrica (levetiracetam) are antiepileptic drugs (AEDs) used to treat partial-onset seizures in adults.

Lyrica is also used to treat partial-onset seizures in children 1 month of age and older.

Side effects of Xcopri and Lyrica that are similar include drowsiness, dizziness, and fatigue/tiredness.

Side effects of Xcopri that are different from Lyrica include double vision and headache.

Side effects of Lyrica that are different from Xcopri include weakness, infection, loss of appetite, and stuffy nose.

Both Xcopri and Lyrica may interact with other antiepileptic drugs (AEDs) and oral contraceptives.

Xcopri may also interact with CYP2B6 and CYP3A substrates, CYP2C19 substrates, other drugs that shorten the QT interval, alcohol, and other CNS depressants.

Lyrica may also interact with digoxin, warfarin, and probenecid.

What Are Possible Side Effects of Xcopri?

Common side effects of Xcopri include:

  • drowsiness,
  • dizziness,
  • fatigue,
  • double vision, and
  • headache

What Are Possible Side Effects of Lyrica?

Common side effects of Lyrica include:

What Is Xcopri?

Xcopri (cenobamate tablets) is an antiepileptic drug (AED) used to treat partial-onset seizures in adult patients.

What Is Lyrica?

Lyrica (pregabalin) is an anti-epileptic drug (anticonvulsant) used for neuropathic (nerve) pain associated with diabetic peripheral neuropathy or postherpetic neuralgia, and for treating partial onset seizures in adults, and fibromyalgia.


What Is Epilepsy? Symptoms, Causes, and Treatments See Slideshow

What Drugs Interact With Xcopri?

Xcopri may interact with other medicines such as:

  • antiepileptic drugs (AEDs),
  • CYP2B6 and CYP3A substrates,
  • CYP2C19 substrates,
  • oral contraceptives,
  • other drugs that shorten the QT interval,
  • alcohol, and
  • other CNS depressants

Tell your doctor all medications and supplements you use and all vaccines you recently received.

What Drugs Interact With Lyrica?

Lyrica may interact with alcohol, other medicines that can make you sleepy (sold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for anxiety), or rosiglitazone.

How Should Xcopri Be Taken?

The recommended initial dosage of Xcopri is 12.5 mg once daily, adjusted to the recommended maintenance dosage of 200 mg once daily.

How Should Lyrica Be Taken?

The recommended dose of Lyrica is 75-600 mg daily. Alcohol and drugs that cause sedation may increase the sedative effects of Lyrica. There are no adequate studies of Lyrica in pregnant women. If you become pregnant, your name may be listed on a pregnancy registry to track the outcome of the pregnancy and to evaluate any effects of Lyrica on the baby. It is unknown if Lyrica passes into breast milk or if it could harm a nursing baby. Breastfeeding while using Lyrica is not recommended.


If you have had a seizure, it means you have epilepsy. See Answer

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SK Biopharmaceuticals Co., Ltd. Xcopri.


Pfizer. Lyrica Prescribing Information.


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