Are Xenleta and Zosyn the Same Thing?
Zosyn is also used to treat many different infections caused by bacteria, such as urinary tract infections (UTIs), bone and joint infections, severe vaginal infections, stomach infections, and skin infections.
Xenleta may interact with strong CYP3A4 inducers or P-gp inducers, strong CYP3A inhibitors or P-gp inhibitors, alprazolam, diltiazem, verapamil, simvastatin, vardenafil, antiarrhythmics, antipsychotics, erythromycin, moxifloxacin, and tricyclic antidepressants.
Zosyn may interact with probenecid, antibiotics, blood thinners, or medications used to prevent blood clots.
What Are Possible Side Effects of Xenleta?
Common side effects of Xenleta include:
- injection site reactions,
- elevated liver enzymes,
- low blood potassium,
- nausea, and
What Are Possible Side Effects of Zosyn?
Common side effects of Zosyn include:
- soreness or
- trouble sleeping (insomnia),
- stomach pain or upset,
- runny nose,
- skin rash or
- itching, or
- vaginal discharge or itching.
Tell your doctor if you have serious side effects of Zosyn including muscle cramps or spasms, swelling of the arms/legs/hands/feet, easy bruising or bleeding, chest pain, confusion, new signs of infection (such as fever, persistent sore throat), severe abdominal or stomach pain, slow/fast/irregular heartbeat, persistent nausea or vomiting, seizures, extreme tiredness, dark or cloudy urine, change in the amount of urine, yellowing eyes or skin, or serious skin reactions (rash, peeling, sores, or blisters).
What Is Xenleta?
What Is Zosyn?
Zosyn (piperacillin and tazobactam for injection) is a combination of two antibiotics used to treat many different infections caused by bacteria, such as urinary tract infections, bone and joint infections, severe vaginal infections, stomach infections, skin infections, and pneumonia. Zosyn is available in generic form.
What Drugs Interact With Xenleta?
Xenleta may interact with strong CYP3A4 inducers or P-gp inducers, strong CYP3A inhibitors or P-gp inhibitors, alprazolam, diltiazem, verapamil, simvastatin, vardenafil, antiarrhythmics, antipsychotics, erythromycin, moxifloxacin, and tricyclic antidepressants. Tell your doctor all medications and supplements you use. Xenleta is not recommended for use during pregnancy; it may harm a fetus. Females of reproductive potential are advised to use effective contraception during treatment with Xenleta and for 2 days after the final dose. It is unknown if Xenleta passes into breast milk. Because of the potential for adverse reactions in nursing infants, breastfeeding is not recommended while using Xenleta. Women should pump and discard breast milk for the duration of treatment with Xenleta and for 2 days after the final dose.
What Drugs Interact With Zosyn?
Zosyn may interact with probenecid, antibiotics, blood thinners, or any other medication used to prevent blood clots. Tell your doctor all medications you use.
How Should Xenleta Be Taken?
How Should Zosyn Be Taken?
The usual total daily dose of Zosyn for adults is 3.375 g every six hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam).
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Nabriva Therapeutics. Xenleta Product Information.
Pfizer. Zosyn Product Information.